Results 251 to 260 of about 171,176 (291)

Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow

Advanced Science, EarlyView.
DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley   +1 more source

<i>Lactobacillus rhamnosus</i> Glory LG12 preventives loperamide-induced constipation in mice by modulating intestinal flora and metabolic pathways. [PDF]

Front Microbiol
Ma W, Lian L, Guo L, Wu Y, Huang L.
europepmc   +1 more source

EETs Reduction Contributes to Granulosa Cell Senescence and Endometriosis‐Associated Infertility via the PI3K/AKT/mTOR Signaling Pathway

Advanced Science, EarlyView.
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin, Weijia Gu, Xiaomei Tong, Mengru Lai, Yi Zhang, Na Liu, Xiaoying Jin, Chao Li, Dong Huang, Feng Zhou, Yongdong Dai, Songying Zhang   +11 more
wiley   +1 more source

Mechanism of Liver Injury during Obstructive Jaundice: Role of Nitric Oxide, Splenic Cytokines, and Intestinal Flora

, 2007
Ji‐Young Hong, Eisuke F. Sato, Keiichi Hiramoto, Manabu Nishikawa, Masayasu Inoue   +4 more
openalex   +2 more sources

Intestinal flora was associated with occurrence risk of chronic non-communicable diseases. [PDF]

World J Gastroenterol
Jiang GH, Li HY, Xie LJ, Fan JY, Li SY, Yu WQ, Xu YT, He ML, Jiang Y, Bai X, Zhou J, Wang X.   +11 more
europepmc   +1 more source

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

Advanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi, Wen Tan, Haochun Jin, Sio I Chan, Wei Li, Si San Lei, Guozhen Cui, Yitao Wang, Dong‐Hua Yang, Zhangfeng Zhong   +9 more
wiley   +1 more source

Inulin alleviates acute alcoholism in mice by enhancing ethanol metabolism and regulating the intestinal flora [PDF]

Zhouya Bai, Honglin Lan, Denglin Luo, Xingguo Li, Yunhui Zhang, Mengyuan Geng, Shaohe Chang   +6 more
openalex   +1 more source

Huangqi Guizhi Wuwu decoction ameliorates myocardial damage in ovariectomized rats by regulating the structure and function of myocardial microvessels and intestinal flora. [PDF]

Microbiol Spectr
Jiang Y, Yang Y, Hu J, Liu Y, Liu H, Zhang Z, Chen Y.   +6 more
europepmc   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

Effects of Long-Term Airport Noise Exposure on Inflammation and Intestinal Flora and Their Metabolites in Mice. [PDF]

Metabolites
Yang J, Wei L, Xia Y, Wang J, Bai Y, Xia Y.   +5 more
europepmc   +1 more source