Results 111 to 120 of about 670,112 (215)

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

High-altitude-induced alterations in intestinal microbiota

Frontiers in Microbiology
In high-altitude environments characterized by low pressure and oxygen levels, the intestinal microbiota undergoes significant alterations. Whether individuals are subjected to prolonged exposure or acute altitude changes, these conditions lead to shifts
Dan Liu, Dan Chen, Jian Xiao, Wei Wang, Li-Juan Zhang, Hui Peng, Chuan Han, Hao Yao   +7 more
doaj   +1 more source

Intestinal Microbiota Metabolism and Atherosclerosis

, 2015
Objective: This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target.
Tian-Xing Liu, Hai-Tao Niu, Shu-Yang Zhang   +2 more
core   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Beta-Glucan modulates monocyte plasticity and differentiation capacity to mitigate DSS-induced colitis

eLife
Trained immunity involves the reprogramming of innate immune cells after an initial exposure, resulting in heightened inflammatory responses to subsequent stimuli and enhanced bactericidal capacity during infection.
Yinyin Lv, Yanyun Fan, Qingxiang Gao, Qiongyun Chen, Yiqun Hu, Lin Wang, Huaxiu Shi, Ermei Chen, Qinyu Xu, Ying Cai, Qingqi Fan, Linying Li, Dan Du, Jianlin Ren, Shih-Chin Cheng, Hongzhi Xu   +15 more
doaj   +1 more source

Research progress on effect of dietary nutrients and feed additives on intestinal microflora of pigs

Siliao yanjiu, 2023
The gut microbiota helps host gut to perform a variety of physiological functions, which plays an important role in improving the intestinal health and performance of pigs. Intestinal microbiota has strong plasticity, which is readily changeable by diet,
ZHAO Huai-bao
doaj  

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Modulation of intestinal microbiota by probiotics and lactulose in children treated with ceftriaxone

, 1998
Modulation of intestinal microbiota by probiotic and lactulose in children treated with ...
BERTAZZONI MINELLI, Elisa, Cinquetti M., BENINI, Anna, ZOPPI, Giuseppe, Bonamini E.   +4 more
core   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

The Function of Probiotics and Prebiotics on Canine Intestinal Health and Their Evaluation Criteria

Microorganisms
Maintaining homeostasis within the intestinal microbiota is imperative for assessing the health status of hosts, and dysbiosis within the intestinal microbiota is closely associated with canine intestinal diseases.
Junliang Xia, Yuling Cui, Yan Guo, Yuwen Liu, Baichuan Deng, Sufang Han   +5 more
doaj   +1 more source