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The human intestinal microbiota
Gastroentérologie Clinique et Biologique, 2010The human intestinal microbiota constitutes a complex ecosystem which is now well recognized for its impact on human health and well-being. It contributes to maturation of the immune system and provides a direct barrier against colonization by pathogens.
J, Doré, G, Corthier
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The normal intestinal microbiota
Current Opinion in Infectious Diseases, 2007Long neglected and considered a difficult ecosystem to study, several developments have recently converged to renew interest in studying the normal gut microbiota. These include molecular methods of studying the microbiota, improved understanding of host-microbe interactions in health and disease, and the potential for therapeutic manipulation of the ...
Julian, Marchesi, Fergus, Shanahan
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Interaction of Intestinal Microbiota with Medications
Current Drug Metabolism, 2023Introduction:: It is well known that the response to and metabolism of the drugs entering the human body varies widely across individuals. One of the reasons is that such interpersonal differences may be related to gut microbes. On one hand, drugs or xenobiotics entering the human body may affect the composition of the gut microbiome; on the other ...
Mengchen Liu +3 more
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Intestinal Microbiota and Obesity
2011The human gut harbors a highly diverse microbial ecosystem of approximately 400 different species, which is characterized by a high interindividual variability. The intestinal microbiota has recently been suggested to contribute to the development of obesity and the metabolic syndrome. Transplantation of gut microbiota from obese mice to nonobese, germ-
Michael, Blaut, Susanne, Klaus
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NeoReviews, 2009
Humans maintain a diverse, dynamic, and complex intestinal microbiota that performs a multitude of vital functions, such as growth and development of the epithelial barrier, stimulation of intestinal angiogenesis, regulation of nutrition, metabolic functions, and education of naïve neonatal innate immunity. After birth, host environment and attributes
Renu Sharma +3 more
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Humans maintain a diverse, dynamic, and complex intestinal microbiota that performs a multitude of vital functions, such as growth and development of the epithelial barrier, stimulation of intestinal angiogenesis, regulation of nutrition, metabolic functions, and education of naïve neonatal innate immunity. After birth, host environment and attributes
Renu Sharma +3 more
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Healthy Aging and İntestinal Microbiota
2018Introduction: Aging; is defined as the deterioration that occurs in physiological functions with the progress of age. The intestinal system consists of a complex structure of approximately 10¹³-10¹4 microorganisms.Human intestinal microbiota has an important role in various metabolic, nutritional, physiological and immunological systems ...
Acar Tek, Nilüfer, Koçak, Tevfik
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Small intestine and microbiota
Current Opinion in Gastroenterology, 2011To highlight the recent studies which have enhanced our appreciation of the composition of the microbiota in the human small intestine and its relevance to the health of the host.In the past number of years, the composition of the microorganisms present in our small intestines has been the subject of greater scrutiny than ever before.
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Assembly of the human intestinal microbiota
Trends in Ecology & Evolution, 2006Complex microbial ecosystems occupy the skin, mucosa and alimentary tract of all mammals, including humans. Recent advances have highlighted the tremendous diversity of these microbial communities and their importance to host physiology, but questions remain about the ecological processes that establish and maintain the microbiota throughout life.
Les, Dethlefsen +3 more
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The intestinal microbiota and microenvironment in liver
Autoimmunity Reviews, 2015The intestinal microbiome plays a significant role in the development of autoimmune diseases, in particular, inflammatory bowel diseases. But the interplay between the intestinal tract and the liver may explain the increased association with autoimmune liver diseases and inflammatory bowel diseases.
Hong-Di, Ma +4 more
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Immune adaptations that maintain homeostasis with the intestinal microbiota
Nature Reviews Immunology, 2010 Humans harbour nearly 100 trillion intestinal bacteria that are essential for health. Millions of years of co-evolution have moulded this human-microorganism interaction into a symbiotic relationship in which gut bacteria make essential contributions to ...
Lora V Hooper, Andrew J Macpherson
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