Results 81 to 90 of about 519,517 (262)

Analyzing the functionality of the human intestinal microbiota by stable isotope probing [PDF]

, 2010
Key words: gut bacteria, dietary carbohydrates, digestion, RNA-SIP, TIM-2, HITChip, human trial The human gastro-intestinal (GI) tract comprises a series of complex and dynamic organs ranging from the stomach to the distal colon, which harbor immense ...
Kovatcheva, P.P.
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Towards a safer probiotic: clbD deletion attenuates EcN-induced DNA damage responses and epithelial inflammatory transcriptional responses

Frontiers in Cellular and Infection Microbiology
Escherichia coli Nissle 1917 (EcN) is widely used as a probiotic and engineering chassis, but its carriage of the pks genomic island raises safety concerns related to the genotoxin colibactin.
Wei-Ming Chen, Wei-Ming Chen, Wei-Ming Chen, Ming-Yang Sun, Ming-Yang Sun, Ming-Yang Sun, Ji-Yuan Ye, Ji-Yuan Ye, Ji-Yuan Ye, De-Cheng Tan, De-Cheng Tan, De-Cheng Tan, Zi-Yi Zhang, Zi-Yi Zhang, Zi-Yi Zhang, Jing-Jing Liu, Jing-Jing Liu   +16 more
doaj   +1 more source

Photo‐Switchable Molecular Module Programming PET Biodegradation in Aquatic Environments

Advanced Functional Materials, EarlyView.
We address the plastic durability paradox by integrating an itaconic acid–derived pyrrolidone module into polymer backbones. Sunlight in water triggers Norrish Type I ring‐opening and hydrophilization, enabling rapid biodegradation into nontoxic minerals.
Mohammad Asif Ali, Jixin Zheng, Satoshi Wakai, Jie Liu, Hidetaka Nomaki, Misato Tsukatani, Noriyuki Isobe, Jingcheng Sang, Yuriko Aoki, Hideo Okamura, Daisuke Sasaki, Chiaki Ogino, Yuzo Yamazaki, Takashi Nishikaze, Kenji Takada, Maiko K. Okajima, Tatsuo Kaneko   +16 more
wiley   +1 more source

Enteric opportunistic infections in patients with inflammatory bowel disease receiving biologic therapies: a retrospective cohort study

Gut Pathogens
Background Biologic therapy has improved outcomes in inflammatory bowel disease (IBD) but may predispose patients to enteric opportunistic infections. Asian data comparing infection risk across biologic classes remain scarce.
Ting-Chieh Huang, Tony Kou, Chia-Jung Kuo, Cheng-Hsun Chiu, Tai-Di Chen, Chien-Ming Chen, Jen-Wei Chou, Tien-Yu Huang, Chen-Wang Chang, Cheng-Tang Chiu, Ming-Yao Su, Yu-Bin Pan, Puo-Hsien Le   +12 more
doaj   +1 more source

Development of the intestinal microbiota in the piglet

The Journal of General and Applied Microbiology, 2005
The intestinal commensal microbiota of monogastricanimals such as humans and pigs comprise hundredsof different types of microorganisms (Conway, 1995;Savage, 1977). In the last several decades, the role ofthe intestinal commensal microbiota in a wide range ofhost’s physiological functions has been increasinglyrecognized (Cummings and Macfarlane, 1997).
Inoue, Ryo, Tsukahara, Takamitsu, Nakanishi, Nobuo, Ushida, Kazunari   +3 more
openaire   +3 more sources

Intestinal microbiota, diet and health [PDF]

British Journal of Nutrition, 2013
The human intestine is colonised by 1013to 1014micro-organisms, the vast majority of which belong to the phyla Firmicutes and Bacteroidetes. Although highly stable over time, the composition and activities of the microbiota may be influenced by a number of factors including age, diet and antibiotic treatment.
Susan E, Power, Paul W, O'Toole, Catherine, Stanton, R Paul, Ross, Gerald F, Fitzgerald   +4 more
openaire   +2 more sources

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

[Intestinal microbiota].

Bulletin de l'Academie nationale de medecine, 2016
The human body normally lives in symbiosis with a considerable microscopic environment present on all interfaces with the external environment; it hosts ten times more microbes (microbiota) that it has somatic or germ cells, representing a gene diversity (microbiome) 100-150 times higher than the human genome. These germs are located mainly in the gut,
Patrice, Debré, Jean-Yves, Le Gall
openaire   +3 more sources

Human milk oligosaccharides: bridging the gap in intestinal microbiota between mothers and infants

Frontiers in Cellular and Infection Microbiology
Breast milk is an essential source of infant nutrition. It is also a vital determinant of the structure and function of the infant intestinal microbial community, and it connects the mother and infant intestinal microbiota.
Wen Sun, Lin Tao, Chen Qian, Pei-pei Xue, Si-si Du, Ying-na Tao   +5 more
doaj   +1 more source