Results 31 to 40 of about 154,954 (267)

Dietary spray-dried plasma improves intestinal morphology of mated female mice under stress condition

Journal of Animal Science and Technology, 2018
Background Stress causes inflammation that impairs intestinal barrier function. Dietary spray-dried plasma (SDP) has recognized anti-inflammatory effects and improvement of gut barrier function. Therefore, the purpose of this study was to investigate the
Yanhong Liu, Jeehwan Choe, Sheena Kim, Byeonghyeon Kim, Joy M. Campbell, Javier Polo, Joe D. Crenshaw, James E. Pettigrew, Minho Song   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Vitamin E Improves Morphology and Absorptive Surface of Small Intestine in Broiler Chickens Reared at High Altitude [PDF]

Poultry Science Journal, 2016
Under high altitude conditions, the effects of vitamin E (α-tocopherol) on growth performance, intestinal morphology (villus size and type), and absorptive surface area of broiler chickens were evaluated. Chickens were fed diets supplemented with 0, 100,
Hassanpour H, Bahadoran S, Borjian N
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Effects of Chinese Gallotannins on Antioxidant Function, Intestinal Health, and Gut Flora in Broilers Challenged with Escherichia coli Lipopolysaccharide

Animals
This experiment was conducted to study the protective effects of dietary Chinese gallotannins (CGT) supplementation against Escherichia coli lipopolysaccharide (LPS)-induced intestinal injury in broilers.
Yuemeng Fu, Peng Yuan, Nadia Everaert, Luke Comer, Shuzhen Jiang, Ning Jiao, Libo Huang, Xuejun Yuan, Weiren Yang, Yang Li   +9 more
doaj   +1 more source

Development of Intestinal Injury and Restoration of Weaned Piglets under Chronic Immune Stress

Antioxidants, 2022
This study aimed to investigate the effects of lipopolysaccharide (LPS)-induced chronic immune stress on intestinal morphology and function, immune system, oxidative status, and mitochondrial function in piglets.
Jiayi Yu, Changbing Zheng, Jie Zheng, Geyan Duan, Qiuping Guo, Peiwen Zhang, Mengliao Wan, Yehui Duan   +7 more
doaj   +1 more source

Morphological features and microbiota of the small intestine

Journal of Siberian Medical Sciences, 2023
a single organ, without a clear division into segments. The problem of intestinal anastomotic leakage has not yet been resolved, and its proportion is from 3.4 to 15.3%, with a mortality rate of up to 18.6%. Identification of the anatomical features of different segments of the small intestine and their contents is of practical importance in surgery ...
А.V. Kuznetsov, О.V. Sorokin, L.Yu. Kostina, M.A. Karpov, А.P. Nadeev, V.V. Dolgov, А.А. Glazkov   +6 more
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source