Results 91 to 100 of about 198,094 (268)

Resveratrol mitigates aspirin-induced intestinal injury in rats in a high-altitude hypoxic environment associated with reducing the expression levels of angiotensin II

BMC Gastroenterology
Background This study aimed to investigate whether the polyphenolic compound resveratrol can protect against intestinal injury induced by aspirin in hypoxic rats associated with the inhibition of angiotensin II (Ang-II), as well as mitigating intestinal ...
Paziliya Abulaiti, Wen Hui Shi, Huan Liu, Ailifeire Tuerxuntayi, Kailibinuer Nuermaimaiti, Zhuo Shuyi Liu, Yingying Xing, Najimangu Rehemutula, Kudelaiti Abdukelimu, Weidong Liu, Jiang Wei Liu, Feng Gao   +11 more
doaj   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

THE PEPTIDASES OF INTESTINAL MUCOSA

Journal of Biological Chemistry, 1944
E L, Smith, M, Bergmann
openaire   +2 more sources

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Discussion of irritable bowel syndrome problem at reports of the 15-th United European Gastroenterological Week (Paris, 2007)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2008
Aim of the review. Discussion of reports of 15-th United European Gastroenterological Week, devoted to irritable bowel syndrome (IBS).Obtained data. In reports devoted to the problem of IBS, main attention was paid to the possible pathogenetic components
A. A. Sheptulin, A. A. Kurbatova
doaj  

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Familial adenomatosis coli: surgical treatment with cellular transplantation

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
Aim of investigation. To develop reconstructed mucosa of the rectum for improvement results of surgical treatment of familial adenomatosis polyposis coli (FAP).Material and methods.
Yu. A. Shelygin, A. M. Kuzminov, D. V. Vyshegorodtsev, L. L. Kapuller, G. T. Sukhikh   +4 more
doaj  

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

Intestinal Metaplasia of the Gastric Mucosa [PDF]

Gastroenterologia, 1955
openaire   +4 more sources