Results 91 to 100 of about 724,233 (307)

Increased glucose uptake by intestinal mucosa and muscularis in hypermetabolic sepsis

, 1991
The purpose of the present study was to determine the following: 1) whether the sepsis-induced increase in glucose uptake was a generalized response along the entire length of the gastrointestinal tract; 2) the relative contribution of the mucosa and ...
G. J. Bagby, C. H. Lang, J. N. Bagwell, J. C. Obih, J. J. Spitzer   +4 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Autophagy and proinflammatory cytokine expression in the intestinal mucosa and mesenteric fat tissue of patients with Crohn's disease

Journal of Coloproctology, 2013
Background: Recently, mesenteric fat has been proposed to play a role in the pathophysiol- ogy of Crohn's disease (CD), as fat hypertrophy is detected close to the affected intestinal area; however, there are few studies regarding autophagy and creeping ...
Raquel Franco Leal, Marciane Milanski, Cláudio Saddy Rodrigues Coy, Mariana Portovedo, Viviane Soares Rodrigues, Andressa Coope, Maria de Lourdes Setsuko Ayrizono, João José Fagundes, Lício Augusto Velloso   +8 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Effects of experimental group, intestinal segment and their interaction on mRNA expression of immune, barrier function and nutrient sensing genes in chicken intestinal mucosa.

, 2019
Effects of experimental group, intestinal segment and their interaction on mRNA expression of immune, barrier function and nutrient sensing genes in chicken intestinal mucosa.
Jagoda Lachmanska (6407783), Arkadiusz Plowiec (3597884), Siria Tavaniello (6407786), Malgorzata Radomska (6407780), Maria Siwek (3597878), Giuseppe Maiorano (6407789), Anna Slawinska (3220077), Aleksandra Dunislawska (3611762)   +7 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Nerve fiber outgrowth is increased in the intestinal mucosa of patients with irritable bowel syndrome

, 2015
Mediators released by the intestinal mucosa of patients with irritable bowel syndrome (IBS) affect the function of enteric and extrinsic sensory nerves, which can contribute to the development of symptoms.
De Ponti Fabrizio, Barbaro Maria Raffaella, Le Berre Scoul Catherine, Aubert Philippe, Neunlist Michel, Stanghellini Vincenzo, Dothel Giovanni, Boudin Hélène, Cremon Cesare, Vasina Valentina, Gargano Luciana, Barbara Giovanni, Bellacosa Lara, Boudin, Hélène, BARBARO, MARIA RAFFAELLA, DOTHEL, GIOVANNI, Neunlist, Michel, Le Berre-Scoul, Catherine, DE GIORGIO, ROBERTO, VASINA, VALENTINA, GARGANO, LUCIANA, Le Berre Scoul, Catherine, STANGHELLINI, VINCENZO, BELLACOSA, LARA, Aubert, Philippe, DE PONTI, FABRIZIO, CREMON, CESARE, BARBARA, GIOVANNI   +27 more
core   +2 more sources

Shenfu injection prolongs survival and protects the intestinal mucosa in rats with sepsis by modulating immune response

The Turkish Journal of Gastroenterology, 2019
Background/Aims: The aim of present study was to assess the protective effects of Shenfu injection (SI) on the intestinal mucosa and its regulation on the mucosal immune responses in rats with sepsis.
Shuifang Jin, Ronglin Jiang, Shu Lei, Liming Jin, Chen Zhu, Wen Feng, Yingying Shen   +6 more
doaj   +1 more source

Acute necrosis of the intestinal mucosa

Gastroenterology, 1982
The association of burns with erosive and necrotic lesions in the gastrointestinal mucosa was first recognized in the early part of the 19th century (l-5). The clinical history of these gastrointestinal complications clearly suggests a common pathogenetic mechanism represented by the state of shock which follows extensive skin burns.
openaire   +2 more sources

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source