Results 101 to 110 of about 992,849 (343)
Chronic intestinal pseudo-obstruction (CIPO) is a rare condition characterized by intestinal obstruction without any restriction or occlusion, that represents the most severe form of gastrointestinal dysmotility.
Haoyan Liang+3 more
doaj
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source
ELECTRIC TREATMENT OF INTESTINAL OBSTRUCTION AND POSTOPERATIVE PARALYSIS OF THE BOWEL [PDF]
William H. Dieffenbach
openalex +1 more source
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella+18 more
wiley +1 more source
Alazar Berhe Aregawi,1 Alemwosen Teklehaimanot Alem,2 Abdulkerim Girma3 1Department of Surgery, Hawassa University Comprehensive Specialized Hospital, Hawassa University, Hawassa, Sidama, Ethiopia; 2Department of Pathology, Hawassa University ...
Aregawi AB, Alem AT, Girma A
doaj
The Advantages of Minimally Invasive Surgery for Peritoneal Adhesions in Children
Background. Laparoscopic surgery has advantages over laparotomy. In pediatric practice, only single studies have been devoted to the leading role of laparoscopy in the treatment of peritoneal adhesions in children; randomized controlled studies have not ...
Elena Yu. Dyakonova+3 more
doaj +1 more source
PREGNANCY COMPLICATED BY VOLVULUS OF THE SIGMOID FLEXURE, CAUSING INTESTINAL OBSTRUCTION [PDF]
Malco Donaldson
openalex +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Intestinal obstruction: Role of multi-slice CT in emergency department
Objective: This article presents the characteristic CT imaging findings for different causes of intestinal obstruction, in correlation with their clinical background in emergency department.
Khaled Aly Matrawy, Mohamed El-Shazly
doaj +1 more source