Results 101 to 110 of about 163,710 (350)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

INTESTINAL OBSTRUCTION [PDF]

, 1916
Jean V. Cooke, F. H. Rodenbaugh, G. H. Whipple   +2 more
openalex   +3 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Congenital mesenteric absence of mid-gut with ileal volvulus: a case report

Journal of Medical Case Reports
Background Transmesenteric hernia caused by mesenteric defects are rare causes of intestinal obstruction in children. Here, we report a rare mesenteric defect, which was completely mesenteric in absence, with the defect extending from the mesenteric root
Jin-Shan Zhang
doaj   +1 more source

ECTOPIC FASCIOLIASIS OR PERITONEAL MALIGNANCY TUMORS? (CASE REPORT) [PDF]

Ectopic fascioliasis usually caused by juvenile Fasciola Spp., but in recent years a few cases of tissue-embedded ova have been reported from different areas. A 79 years old Iranian man resident in Ardabil province, complained with abdominal pain, nausea
رامزی, فاطمه, محمدی قلعه بین, بهنام, چینی فروش, میرمهدی   +2 more
core  

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Generation of an induced pluripotent stem cell line (FDCHi008-A) from an infant with chronic intestinal pseudo-obstruction

Stem Cell Research, 2023
Chronic intestinal pseudo-obstruction (CIPO) is a rare condition characterized by intestinal obstruction without any restriction or occlusion, that represents the most severe form of gastrointestinal dysmotility.
Haoyan Liang, Weina Zhu, Chun Shen, Haitao Zhu   +3 more
doaj  

Intestinal Obstruction Due to Food [PDF]

, 1950
Neil Ward-McQuaid
openalex   +1 more source

Extensive small bowel gangrene at mid-term pregnancy with fruitful outcome [PDF]

, 2017
Intestinal obstruction during pregnancy is very rare. The mechanical intestinal obstruction was mostly due to adhesion from previous surgery.  Pregnancy may mask the symptoms of intestinal obstruction, and virgin abdomen adds to the ambiguity of the ...
Alsareii, Saeed A., Elbashir, Abdulhadi M., Mustafa, Sana B.   +2 more
core   +2 more sources