Results 61 to 70 of about 163,710 (350)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
A Study on Clinical Profile & Management of Acute Intestinal Obstruction [PDF]
Acute intestinal obstruction is a failure of aboral progression of intestinal contents. The overall mortality and morbidity of bowel obstruction is substantial.
Abhijeet Patil, Dhirendra Wagh
doaj
Surgical treatment of colorectal cancer complicated with acute intestinal obstruction
Background. The main reason for urgent complications of colon cancer is an acute intestinal obstruction (AIO). This is complex pathological condition in 90 % of cases caused by colorectal cancer (CRC).Objective – to evaluate radicality of the performed ...
S. N. Schaeva
doaj +1 more source
Paraduodenal hernia as a reason for small intestine obstruction: Report of a case [PDF]
Internal hernia represents only a small fraction of the patients with intestinal obstruction, however 50% of paraduodenal hernia present as an acute intestinal obstruction.
Akhavan Z,
core
Unusual cause of mechanical ileus: abdominal cocoon syndrome [PDF]
A 38-year-old black male patient was admitted with diarrhea and nausea over two days and aggravating pain in the meso- and epigastium that resolved after urination.
Ceulemans, Laurens J+5 more
core +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Crohn’s Disease Complicated by Rare Types of Intestinal Obstruction: Two Case Reports
Intestinal obstruction is one of the most common complications of Crohn’s disease (CD), jeopardizing the quality of life of patients. Numerous factors may contribute to intestinal obstruction in CD.
Kai Xia+9 more
doaj +1 more source
A Case Report: Intestinal Obstruction Due to Acute Appendicitis [PDF]
Appendicitis has always been the most common surgical case in our daily practices; however, appendicitis presenting mechanical intestinal obstruction is quite rare and it has never been reported in Immanuel Hospital. In this report we present a young man
Pangayoman, R. A. (Roys)
core
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Managing constipation in adults with co-morbidities [PDF]
Constipation can be described in a number of ways but in general it is related to straining, reduced frequency of defecation and/or a sensation of incomplete bowel emptying.
Gardiner, Anji, Hilton, Andrea
core +1 more source