Results 61 to 70 of about 992,849 (343)
Desmoid tumour: a rare etiology of intestinal obstruction
The Pan African Medical Journal, 2015 Intestinal obstruction is a frequently encountered entity in surgical practice. The signs and symptoms, many a times, are suggestive of the level of obstruction, making the diagnosis of obstruction evident.
Gaurav Aggarwal +3 more
doaj +1 more source
Surgical treatment of colorectal cancer complicated with acute intestinal obstruction
Тазовая хирургия и онкология, 2016 Background. The main reason for urgent complications of colon cancer is an acute intestinal obstruction (AIO). This is complex pathological condition in 90 % of cases caused by colorectal cancer (CRC).Objective – to evaluate radicality of the performed ...
S. N. Schaeva
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Etiological Spectrum of Dynamic Intestinal Obstruction
Gomal Journal of Medical Sciences, 2004 Background: Intestinal obstruction is a common and potentially dangerous surgical emergency with high morbidity and mortality if managed inappropriately. It is essential to distinguish between its various types. The aim of this study was to determine the
Tariq Wahab Khanzada +2 more
doaj
Rheumatology, 2016 OBJECTIVE Intestinal pseudo-obstruction is a rare gastrointestinal complication in patients with SSc without large studies examining its prevalence or outcomes.
A. Valenzuela +6 more
semanticscholar +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
FEBS Letters, EarlyView.Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos +3 more
wiley +1 more source
Molecular Neurodegeneration, 2014 BackgroundIntraneuronal inclusions of TAR DNA-binding protein 43 (TDP-43) have been found in the majority of Amyotrophic Lateral Sclerosis (ALS) patients. Mutations in the gene encoding TDP-43 cause familial ALS.
Sarah Herdewyn +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
EXPERIMENTAL INTESTINAL OBSTRUCTION [PDF]
Archives of Internal Medicine, 1918 REVIEW OF THE LITERATURE The following experimental work was begun in the summer of 1915, at the suggestion of Dr. A. J. Carlson, as a further contribution toward the explanation of the cause of death in acute ileus, or high intestinal obstruction.
Leo L. J. Hardt, Frank L. South
openaire +3 more sources
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source