Results 61 to 70 of about 668,258 (255)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

An Algorithm for Analyzing Computed Tomography Images in Case of Suspected Strangulation in Adhesive Intestinal Obstruction

open access: yesНеотложная медицинская помощь
Introduction. Adhesive intestinal obstruction is responsible for up to 2.4% of all laparotomies. The choice of patient management strategy directly depends on whether there are indications (including CT findings) of intestinal obstruction and/or ischemia
O. V. Sementsova   +3 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Research progress on the pathogenesis of intestinal obstruction

open access: yes结直肠肛门外科
Intestinal obstruction is a common acute abdominal emergency worldwide, with an incidence of approximately 231.393 per 100,000 in China. The etiology is complex and can be classified into three types: mechanical, dynamic, and vascular intestinal ...
Zheng Xunri, Long Fei, Zhang Yi
doaj   +1 more source

Neonatal intestinal obstruction

open access: yes, 2005
While the causes of newborn intestinal obstruction are diverse, a systematic approach can be used to differentiate the most common causes. The antenatal history, initial presentation, physical examination, and plain radiographs frequently can establish ...
Burd, Randall S., Randall S. Burd
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Uterine Rotation: A Cause of Intestinal Obstruction [PDF]

open access: yes, 2013
Intestinal obstruction is an uncommon surgical emergency during pregnancy that affects seriously the prognosis of gestation. The underlying cause can be identified in the majority of cases and usually consists of adhesions secondary to previous abdominal
Isidoro Narbona   +5 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

A rare cause of intestinal obstruction: ileosigmoid knot [PDF]

open access: yes, 2016
Intestinal obstruction is common surgical emergency; ileosigmoid knot is a rare cause of intestinal  obstruction (a loop ileum and sigmoid colon twisted around each other in a knot). We recorded a three cases in HASSAN II hospital in the last 3 years.Key
Morad, Oussaid   +7 more
core  

Intestinal Obstruction During Pregnancy

open access: yes, 2006
Intestinal obstruction is a rare cause of acute abdominal pain during pregnancy. We reviewed and analyzed the medical records of four pregnant women with intestinal obstruction, treated at the Department of Surgery in the Kaohsiung Medical University ...
Jan-Sing Hsieh   +11 more
core   +1 more source

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