Results 81 to 90 of about 163,710 (350)

A Case of Intestinal Obstruction in Pregnancy Diagnosed by MRI and Treated by Intravenous Hyperalimentation

Case Reports in Obstetrics and Gynecology, 2016
Intestinal obstruction in pregnancy is rare and is mainly caused by prior pelvic surgery. We herein report a case of intestinal obstruction in a pregnant female with a history of laparoscopic myomectomy, who presented with hypogastric pain, abdominal ...
Atsushi Daimon, Yoshito Terai, Yoko Nagayasu, Atsuko Okamoto, Takumi Sano, Yusuke Suzuki, Kazuyoshi Kanki, Daisuke Fujita, Masahide Ohmichi   +8 more
doaj   +1 more source

Chylolymphatic cyst as a rare cause of acute intestinal obstruction in infants

Annals of Pediatric Surgery, 2023
Background Chylolymphatic cysts are benign pathology in lymphatic vessels due to obstruction in the lymphatic system. Their incidence is still unknown. However, they account for approximately 3 to 9% of all pediatric lymphangiomas.
Ahmed K. Ali, Islam M. Abdelhamid, Abdelrahman Hamdy Mohamed, Tarek Abdelazeem Sabra   +3 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Apple-peel atresia presenting as foetal intestinal obstruction

African Journal of Paediatric Surgery, 2011
Apple-peel atresia or Type 3 jejuno-ileal atresia (JIA) is an uncommon cause of foetal intestinal obstruction. Bowel obstruction in the foetus is diagnosed on the prenatal ultrasonography only in 50% cases.
Ashok Yadavrao Kshirsagar, Sushma Rajaram Desai, Mayur Anant Nagvekar, Gaurav Om Prakash Vasisth   +3 more
doaj   +1 more source

A case of large bowel obstruction secondary to twin pregnancy [PDF]

, 2017
No abstract ...
Mansouri, David, McCarter, Douglas, McMillan, Marcus, Metcalfe, Roseanna, Nelson, Scott M.   +4 more
core   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Staged surgical treatment of apple peel intestinal atresia

Journal of Pediatric Surgery Case Reports, 2019
Apple peel atresia is an uncommon cause of intestinal obstruction. The authors report a case of a 36 weeks preterm girl, presenting with a fetal intestinal obstruction on prenatal ultrasonography, that was intraoperatively diagnosed with small bowel ...
Jalles Filipa, Morgado Mariana, Janeiro Marta, Gonçalves Miroslava   +3 more
doaj  

Chronic descending colon obstruction caused by congenital band

Journal of Pediatric Surgery Case Reports, 2022
A congenital band is an infrequent abnormality. Intestinal obstruction caused by an anomalous congenital band is very rare in children. Herein, we present the case of a 6-year-old patient with intestinal obstruction due to a congenital band.
Waseem Shater, Gulan Maree, Ali Farid Alelayan, Bardisan Gawrieh, Wajih Ali   +4 more
doaj  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source