Results 31 to 40 of about 726,579 (340)

Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response

Neoplasia: An International Journal for Oncology Research, 2017
Intestinal tumorigenesis in the ApcMin/+ model is initiated by aberrant activation of Wnt pathway. Increased IL-4 expression in human colorectal cancer tissue and growth of colon cancer cell lines implied that IL-4–induced Stat6-mediated tumorigenic ...
Asha Jayakumar, Alfred L.M. Bothwell
doaj   +1 more source

Inhibition of intestinal adenoma formation in APC(Min/+) mice by Riccardin D, a natural product derived from liverwort plant Dumortiera hirsuta. [PDF]

PLoS ONE, 2012
BACKGROUND: Mutation of tumor suppressor gene, adenomatous polyposis coli (APC), is the primary molecular event in the development of most intestinal carcinomas.
Hui-Ping Liu, Zu-Hua Gao, Shu-Xiang Cui, De-Fu Sun, Yan Wang, Cui-Rong Zhao, Hong-Xiang Lou, Xian-Jun Qu   +7 more
doaj   +1 more source

Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up [PDF]

, 2015
Objective. Atrophic gastritis (AG) is a risk condition for gastric cancer and type I gastric carcinoids. Recent studies assessing the overall risk of gastric cancer and carcinoids in AG at long-term follow up are lacking.
Annibale, Bruno, Corleto, Vito Domenico, DI GIULIO, Emilio, Esposito, Gianluca, Lahner, Edith, Pilozzi, Emanuela, Purchiaroni, Flaminia   +6 more
core   +2 more sources

Duodenal carcinoid tumour – a case report [PDF]

, 2020
Duodenal carcinoids are rare tumours of the small intestine with heterogenous clinical and pathological characteristics. The long-term prognosis is very good if discovered in the early stages.
Alexescu, Teodora Gabriela, Buchman, Cristina, Domsa, Iacob, Milaciu, Mircea, Negrean, Vasile, Orasan, Olga Hilda, Para, Ioana, Perne, Mirela Georgiana   +7 more
core   +2 more sources

HYPERPLASTIC GASTRIC POLYPS PRESENTING WIT MASSIVE UPPER GASTRO-INTESTINAL BLEED

Journal of Nepal Medical Association, 2004
A 39 year old man presented with massive upper Gastro-intestinal (GI) Bleed of 4 days duration. There was h/o chronic epigastric pain of 6 months duration. Upper Gl Endoscopy revealed a large polypoid mass of 6 cms x 5 cms in diameter on anterior wall of
Prahlad Karki, J A Ansari, A Sinha, S Rijal   +3 more
doaj   +1 more source

SHH medulloblastoma and very early onset of bowel polyps in a child with PTEN hamartoma tumor syndrome

Frontiers in Molecular Neuroscience, 2023
Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) is a cancer predisposition syndrome characterized by an increased risk of developing benign and malignant tumors, caused by germline pathogenic variants of the PTEN tumour suppressor ...
Anna Maria Caroleo, Silvia Rotulo, Emanuele Agolini, Marina Macchiaiolo, Luigi Boccuto, Manila Antonelli, Giovanna Stefania Colafati, Antonella Cacchione, Giacomina Megaro, Andrea Carai, Maria Antonietta De Ioris, Mariachiara Lodi, Assunta Tornesello, Valeria Simone, Filippo Torroni, Giuseppe Cinalli, Angela Mastronuzzi   +16 more
doaj   +1 more source

Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer : diagnostic and therapeutic potential [PDF]

, 2015
Caspases are a group of proteolytic enzymes involved in the co-ordination of cellular processes, including cellular homeostasis, inflammation and apoptosis.
Caiazza, F, Creagh, EM, Doherty, GA, Fay, J, Flood, B, Heetun, Z, Kay, E, Laukens, Debby, Mills, KHG, O'Grady, A, Oficjalska, K, Ryan, EJ, Sheahan, K   +12 more
core   +2 more sources

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Mouse models of colorectal cancer. [PDF]

, 2011
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip, Tong, Yunguang, Yang, Wancai   +2 more
core   +2 more sources

Melaena with Peutz-Jeghers syndrome: a case report [PDF]

, 2010
Introduction: Peutz-Jeghers syndrome (PJS) is a rare familial disorder characterised by mucocutaneous pigmentation, gastrointestinal and extragastrointestinal hamartomatous polyps and an increased risk of malignancy. Peutz-Jeghers polyps in the bowel may
Amitabh Palit, DM Nagorney, Ernie Ruban, FM Giardiello, George Mathew, HM Sokmen, IR Schreibman, JD Cunningham, JL Buck, JM Chiang, John R Morrissey, JP Harris, K Akimaru, K Celinski, KM Zbuk, M Barussaud, M Pitiakoudis, NM Lindor, O Blatchford, PP Ter Borg, Ramlal Nangalia, RJ Atkinson, Sayantan Bhattacharya, Sunondo R Mahapatra, TO Kovacs, VC Petersen, Vijay Jadhav   +26 more
core   +3 more sources