Results 71 to 80 of about 726,579 (340)

Multitargeted Low-Dose GLAD Combination Chemoprevention: A Novel and Promising Approach to Combat Colon Carcinogenesis [PDF]

, 1967
Preclinical studies have shown that gefitinib, licofelone, atorvastatin, and α-difluoromethylornithine (GLAD) are promising colon cancer chemopreventive agents.
Altaf Mohammed, Naveena B Janakiram, Misty Brewer, Krishna Vedala, Vernon E Steele, Chinthalapally V Rao, Ferlay, Half, Moser, Preston, Corpet, Reddy, Reddy, Kawamori, Swamy, Rao, Bertagnolli, Mohammed, Janakiram, Perez, Lao, Zhou, Gerner, Suh, Sporn, Frei, Nigro, Li, Zell, Ignatenko, Meyskens, Reddy, Ali, Narisawa, Narisawa, Poynter, Sacks, Pederson, Agarwal, Swamy, Shaw, Gavert, Baselga, Jacoby, Erdman, Yerushalmi, Dougherty, Kaminska, Ueda, Giles, Harris, Fantini, Akagi, Petersen, Lee   +54 more
core   +2 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Endoscopy : an evolving speciality [PDF]

, 2005
The practice of endoscopy has been rapidly changing due to new emerging technologies and novel techniques. There has been more focus on colonoscopy training with the development of structured programmes including simulators.
Arebi, Naila, Saunders, Brian P., Surgical Procedures, Endoscopic   +2 more
core  

Superpixel Based Segmentation and Classification of Polyps in Wireless Capsule Endoscopy

, 2017
Wireless Capsule Endoscopy (WCE) is a relatively new technology to record the entire GI trace, in vivo. The large amounts of frames captured during an examination cause difficulties for physicians to review all these frames.
Maghsoudi, Omid Haji
core   +1 more source

The prevalence of high dysplastic colonic adenomatous polyps in a 3 year endoscopic retrospective study from a single clinical center [PDF]

, 2017
Introduction: Many colon neoplastic tumors come from the malignancy of adenomatous polyps (70%-90%) that were not timely diagnosed in order to be resected.
Moldovan, Cosmin A., Septimiu, Alexandru C., Ungureanu, Florin D.   +2 more
core   +3 more sources

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Generalization Enhancement and Dynamic Perception of Colorectal Polyp Segmentation Network

Shuju Caiji Yu Chuli
With the rapid development of computer‑aided medical diagnosis systems and medical image segmentation technologies， the performance of colorectal endoscopy has been significantly improved， effectively helping clinicians make quick and accurate judgments ...
WANG Sen, SHI Caijuan, CAI Ao, WANG Rui, YU Xinyang, CHENG Xudong, CHEN Weibin   +6 more
doaj   +1 more source

Secondary Colo-Colic Intussusception Caused by Giant Polyp of Sigmoid Colon in a 5-Year-Old Girl

Case Reports in Gastroenterology, 2023
Intussusception is common in infants and young children. The most common type is small intestinal intussusception or ileo-colic intussusception. Colonic intussusception is rare.
Tan Haizhi, Xiao Xiaobing, Deng Jianrong
doaj   +1 more source

Comparative Validation of Polyp Detection Methods in Video Colonoscopy: Results from the MICCAI 2015 Endoscopic Vision Challenge [PDF]

, 2017
Colonoscopy is the gold standard for colon cancer screening though still some polyps are missed, thus preventing early disease detection and treatment. Several computational systems have been proposed to assist polyp detection during colonoscopy but so ...
Angermann, Quentin, Balasingham, Ilangko, Bernal, Jorge, Brandao, Patrick, Chen, Hao, Choi, Sungbin, Cordova, Henry, Debard, Quentin, Dray, Xavier, Fernandez-Esparrach, Gloria, Gurudu, Suryakanth R., Histace, Aymeric, Liang, Jianming, Maier-Hein, L., Matuszewski, Bogdan J., Pogorelov, Konstantin, Romain, Olivier, Rustad, Bjorn, Sanchez, F. Javier, Sanchez-Montes, Cristina, Speidel, Stefanie, Stoyanov, Danail, Tajbakhsh, Nima, Yu, Lequan   +23 more
core   +3 more sources

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source