Results 101 to 110 of about 112,967 (218)

Blood‐Based Circulating Tumor DNA Assays for Early Colorectal Cancer Detection: A Systematic Review of Performance in Asymptomatic Screening Populations

open access: yesInternational Journal of Cancer, Volume 159, Issue 4, Page 1028-1041, 15 August 2026.
Early detection of colorectal cancer via population‐based screening programs can reduce incidence and mortality, but current screening approaches are limited. This systematic review evaluated the screening potential of blood‐based circulating tumor DNA assays in asymptomatic screening populations.
Caroline Ledertoug Kahn   +4 more
wiley   +1 more source

Differences in Biologic Clinical Trials for Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 769-777, August 2026.
Key Points In recent years, several biologics targeting Type 2 inflammation have been developed for treating chronic rhinosinusitis with nasal polyps (CRSwNP). These have been studied in registrational randomized controlled trials (RCTs), which vary in their patient populations, trial design, endpoints, geography, timing, or data‐handling processes ...
Marjolein Cornet   +10 more
wiley   +1 more source

Adenomatous polyps of the small intestine

open access: yesJournal of British Surgery, 1953
W R, HUNTER, W A, WILSON
openaire   +2 more sources

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2885-2898, August 2026.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

Evidence‐Based Nursing Management During Mavacamten Therapy in an 89‐Year‐Old Patient With Symptomatic Hypertrophic Obstructive Cardiomyopathy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT In older patients receiving mavacamten, a reduction in NT‐proBNP levels may coexist with persistent severe LVOTO. Nurses should interpret this biomarker–echocardiography discordance as a safety signal and maintain structured cardiovascular surveillance rather than assuming treatment success based solely on biomarker improvement.
Feifei Wang
wiley   +1 more source

Comparative Performance of Pap Smear and Colposcopy in Cervical Cancer Screening Among Women With Abnormal Cervical Findings in Central India: A Prospective Observational Study

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Cervical cancer remains a leading cause of death among women worldwide, particularly in low‐ and middle‐income countries. This study aimed to evaluate and compare the effectiveness of Pap smear and colposcopy in detecting cervical abnormalities in women with unhealthy cervices and correlate findings with biopsy results.
Bhukya Priyanka   +6 more
wiley   +1 more source

Luteal phase stimulation versus follicular phase stimulation in poor ovarian responders: A systematic review and a meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 174, Issue 2, Page 608-620, August 2026.
Abstract Background Poor ovarian response (POR) complicates a substantial proportion of in vitro fertilization (IVF) cycles, frequently causing cycle cancellation and suboptimal reproductive outcomes. Conventional follicular‐phase ovarian stimulation (FPOS) protocols often yield limited results, prompting the evaluation of alternative strategies such ...
Vittorio Agrifoglio   +8 more
wiley   +1 more source

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao   +4 more
wiley   +1 more source

Intususcepción íleo-ileal secundaria a un pólipo fibrinoide inflamatorio

open access: yesRevista Colombiana de Cirugía
Introducción. El pólipo fibrinoide inflamatorio es una lesión inflamatoria no neoplásica que se presenta especialmente en el estómago, aunque puede ocurrir en cualquier parte del tubo digestivo, en donde puede ocasionar episodios de intususcepción y ...
Carlos Andrés Calle   +3 more
doaj  

Comparison of the Application Value of 4‐Dimensional Hysterosalpingo‐Contrast Sonography and X‐Ray Hysterosalpingography in Intrauterine Insemination

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 8, Page 1655-1661, August 2026.
Objectives To compare the application value of 4‐dimensional hysterosalpingo‐contrast sonography (4D‐HyCoSy) and x‐ray hysterosalpingography (HSG) in intrauterine insemination (IUI) patients. Methods In this retrospective study, a total of 725 infertile patients who underwent IUI in Ganzhou Maternal and Child Health Hospital from January 2023 to June ...
Yongyu Xie   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy