Results 101 to 110 of about 112,967 (218)
Early detection of colorectal cancer via population‐based screening programs can reduce incidence and mortality, but current screening approaches are limited. This systematic review evaluated the screening potential of blood‐based circulating tumor DNA assays in asymptomatic screening populations.
Caroline Ledertoug Kahn +4 more
wiley +1 more source
Key Points In recent years, several biologics targeting Type 2 inflammation have been developed for treating chronic rhinosinusitis with nasal polyps (CRSwNP). These have been studied in registrational randomized controlled trials (RCTs), which vary in their patient populations, trial design, endpoints, geography, timing, or data‐handling processes ...
Marjolein Cornet +10 more
wiley +1 more source
Adenomatous polyps of the small intestine
W R, HUNTER, W A, WILSON
openaire +2 more sources
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong +6 more
wiley +1 more source
ABSTRACT In older patients receiving mavacamten, a reduction in NT‐proBNP levels may coexist with persistent severe LVOTO. Nurses should interpret this biomarker–echocardiography discordance as a safety signal and maintain structured cardiovascular surveillance rather than assuming treatment success based solely on biomarker improvement.
Feifei Wang
wiley +1 more source
ABSTRACT Background Cervical cancer remains a leading cause of death among women worldwide, particularly in low‐ and middle‐income countries. This study aimed to evaluate and compare the effectiveness of Pap smear and colposcopy in detecting cervical abnormalities in women with unhealthy cervices and correlate findings with biopsy results.
Bhukya Priyanka +6 more
wiley +1 more source
Abstract Background Poor ovarian response (POR) complicates a substantial proportion of in vitro fertilization (IVF) cycles, frequently causing cycle cancellation and suboptimal reproductive outcomes. Conventional follicular‐phase ovarian stimulation (FPOS) protocols often yield limited results, prompting the evaluation of alternative strategies such ...
Vittorio Agrifoglio +8 more
wiley +1 more source
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao +4 more
wiley +1 more source
Intususcepción íleo-ileal secundaria a un pólipo fibrinoide inflamatorio
Introducción. El pólipo fibrinoide inflamatorio es una lesión inflamatoria no neoplásica que se presenta especialmente en el estómago, aunque puede ocurrir en cualquier parte del tubo digestivo, en donde puede ocasionar episodios de intususcepción y ...
Carlos Andrés Calle +3 more
doaj
Objectives To compare the application value of 4‐dimensional hysterosalpingo‐contrast sonography (4D‐HyCoSy) and x‐ray hysterosalpingography (HSG) in intrauterine insemination (IUI) patients. Methods In this retrospective study, a total of 725 infertile patients who underwent IUI in Ganzhou Maternal and Child Health Hospital from January 2023 to June ...
Yongyu Xie +3 more
wiley +1 more source

