Results 41 to 50 of about 112,503 (234)

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

The Importance of Simultaneous Surgical and Endoscopic Polypectomies in Peutz-Jeghers Syndrome: A Case Report

İstanbul Medical Journal, 2020
Peutz-Jeghers syndrome may be presented with gastrointestinal and extra-intestinal malignancies. Herein, we report a case of Peutz-Jeghers syndrome with a malignant intestinal polyp accompanied by synchronous multiple hamartomatous gastrointestinal ...
Damla Beyazadam, Tunç Eren, Aman Gapbarov, Hatice Şeneldir, İbrahim Ali Özemir, Özgür Ekinci, Orhan Alimoğlu   +6 more
doaj   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

Colonoscopia como método diagnóstico e terapêutico das moléstias do instestino grosso: análise de 2.567 exames Colonoscopy as a diagnostic and therapeutic method of the large bowel diseases: analysis of 2,567 exams

Arquivos de Gastroenterologia, 2005
RACIONAL: Com o surgimento das fibras ópticas na área médica, houve grande avanço tecnológico na observação do aparelho digestivo, com a introdução dos endoscópios flexíveis, usados anteriormente para o trato digestivo superior.
Sergio Carlos Nahas, Carlos Frederico Sparapan Marques, Sérgio Alonso Araújo, Adilson Akihide Aisaka, Caio Sérgio Rizkallah Nahas, Rodrigo Ambar Pinto, Desidério Roberto Kiss   +6 more
doaj   +1 more source

Atrophic gastritis rather than Helicobacter pylori infection can be an independent risk factor of colorectal polyps: a retrospective study in China

BMC Gastroenterology, 2023
Background Colonoscopy is considered the most effective screening method for colorectal polyps. However, the longevity and complexity of the procedure makes it less desirable to screen for colorectal polyps in the general population.
Zhang Shao-hua, Ren Lin-lin, Su Shen, Tang Yun-he, Tian Zi-bin, Liu Yi, Mao Tao   +6 more
doaj   +1 more source

Roux‐en‐Y gastrojejunostomy and jejunojejunostomy for pyloric obstruction bypass in a horse and a foal

Equine Veterinary Journal, EarlyView.
Abstract Background Gastric outflow obstruction in horses is a rare but challenging condition, often resulting from either congenital anomalies or acquired lesions such as chronic ulceration or pyloric polyps. Conventional surgical bypass procedures, including gastrojejunostomy (GJ) or gastroduodenostomy and less commonly duodenojejunostomy, can ...
Marco Gandini, Nico Bolz, Christian Czech, Myria Hartman, Gessica Giusto   +4 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Blood‐Based Circulating Tumor DNA Assays for Early Colorectal Cancer Detection: A Systematic Review of Performance in Asymptomatic Screening Populations

International Journal of Cancer, EarlyView.
Early detection of colorectal cancer via population‐based screening programs can reduce incidence and mortality, but current screening approaches are limited. This systematic review evaluated the screening potential of blood‐based circulating tumor DNA assays in asymptomatic screening populations.
Caroline Ledertoug Kahn, Maria Wissing Rasmussen, Jakob Kleif, Inge Søkilde Pedersen, Christina Therkildsen   +4 more
wiley   +1 more source

Introduction of digital chromoendoscopy for classification of colonic lesions and assessment of experience gain in a tertiary healthcare hospital

Revista do Colégio Brasileiro de Cirurgiões
Introduction: Colonoscopy is effective in reducing mortality by detecting and removing polyps, but invasive procedures remain common. New techniques, such as the NICE classification with Narrow-band Imaging (NBI), help predict the histology of polyps ...
VITOR COURI BLASSIOLI, LUIZA CADAVAL ROCHA, GUILHERME LOPES MACHADO, LUCAS ALVES BESSA CARDOSO, MARINA BARBABELA GRISOLIA DE OLIVEIRA, RODRIGO ALMEIDA PAIVA, FABIO LOPES QUEIROZ, ANTÔNIO LACERDA FILHO   +7 more
doaj   +2 more sources

Dietary Feeding of Grape Seed Extract Prevents Intestinal Tumorigenesis in APCmin/+ Mice

Neoplasia: An International Journal for Oncology Research, 2010
Chemopreventive effects and associated mechanisms of grape seed extract (GSE) against intestinal/colon cancer development are largely unknown. Herein, we investigated GSE efficacy against intestinal tumorigenesis in APCmin/+ mice.
Balaiya Velmurugan, Rana P. Singh, Nidhi Kaul, Rajesh Agarwal, Chapla Agarwal   +4 more
doaj   +1 more source