Results 51 to 60 of about 112,967 (218)

Rising Incidence and Mortality of Colorectal Cancer Among Younger Adults: A Population‐Based Study in Taiwan, 1994–2018

open access: yesInternational Journal of Cancer, EarlyView.
Colorectal cancer incidence and mortality have increased in the Asia‐Pacific region over the past three decades. This population‐based study in Taiwan suggests a shift of the colorectal cancer burden towards the younger generations. An age–period–cohort model revealed higher annual increases in incidence (3.58%) and mortality (1.0%) rates among ...
Yun‐Chen Tsai   +3 more
wiley   +1 more source

Oral and Maxillofacial Considerations in Gardner's Syndrome

open access: yesInternational Journal of Medical Sciences, 2012
Gardner's Syndrome is a variant of familial adenomatosis polyposis (FAP) with a triad consisting of polyps of the colon, multiple osteomas and surface tumors of soft and hard tissue.
Abdulkadir Burak Cankaya, Mehmet Ali Erdem, Sabri Cemil Isler, Muhsin Cifter, Vakur Olgac, Cetin Kasapoglu, Cuneyt Korhan Oral
doaj  

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad   +5 more
wiley   +1 more source

Classical presentation of Gardner's syndrome in an Indian patient: A case report

open access: yesContemporary Clinical Dentistry, 2016
Gardner's syndrome is an autosomal dominant disease characterized by the presence of colonic polyposis, osteomas, and a multitude of soft-tissue tumors.
Priyanka Verma   +3 more
doaj   +1 more source

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

open access: yesInterdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang   +13 more
wiley   +1 more source

Dietary Feeding of Grape Seed Extract Prevents Intestinal Tumorigenesis in APCmin/+ Mice

open access: yesNeoplasia: An International Journal for Oncology Research, 2010
Chemopreventive effects and associated mechanisms of grape seed extract (GSE) against intestinal/colon cancer development are largely unknown. Herein, we investigated GSE efficacy against intestinal tumorigenesis in APCmin/+ mice.
Balaiya Velmurugan   +4 more
doaj   +1 more source

Clinical and genetic features of pediatric hereditary polyposis syndromes in Israel: A nationwide multicenter cohort

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Hereditary polyposis syndromes in children are rare, heterogeneous disorders associated with significant morbidity and long‐term risk of malignancy. Current data on their presentation, management, and outcomes in pediatric populations remain limited.
Shlomi Cohen   +9 more
wiley   +1 more source

Immunohistochemical study of MUC5AC, MUC1, MUC2, Cdx-2 in hyperplastic polyps and intestinal-type gastric adenocarcinoma

open access: yesZaporožskij Medicinskij Žurnal, 2017
Aim – to study the features of MUC1, MUC2, MUC5AC, Cdx-2 immunohistochemical expression in hyperplastic polyps and intestinal-type gastric adenocarcinoma, and their relationships with the proliferation and apoptosis markers expression levels, EGFR and ...
V. A. Tumanskiy, T. A. Khrystenko
doaj   +1 more source

A case report of Peutz–Jeghers syndrome in a child with Crohn's disease

open access: yesJPGN Reports, EarlyView.
Abstract Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by hamartomatous polyps and mucocutaneous hyperpigmented freckles, whereas Crohn's disease (CD) is a condition characterized by chronic intestinal inflammation. Here, we present a rare case report of an 11‐year‐old male who presented with both CD and PJS.
Hasala Rannulu   +5 more
wiley   +1 more source

Gastric and small intestinal traditional serrated adenomas: a detailed morphologic and immunohistochemical analysis

open access: yesThe Turkish Journal of Gastroenterology, 2020
Background/Aims: TSAs, despite their low incidence in colorectum, may originate in other parts of gastrointestinal (GI) tract, including stomach and small intestine. Malignant transformation for upper GI TSAs has recently been reported in the literature.
Saba Kiremitçi   +3 more
doaj   +1 more source

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