Results 171 to 180 of about 10,784 (245)

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Surgical and Therapeutic Interventions for Chronic Intestinal Pseudo-obstruction: A Scoping Review. [PDF]

J Neurogastroenterol Motil
Dalby C, Shen T, Thélin C, Ganam S, Velanovich V, Sujka J.   +5 more
europepmc   +1 more source

Tetrazine Ligation in Living Systems: Beyond Fast Kinetics to Effective Bioorthogonality

Chemistry – A European Journal, EarlyView.
Rapid reaction kinetics (k2) alone do not ensure successful tetrazine ligation in living systems. This review introduces ‘effective orthogonality’—focusing on chemical survival, availability, and encounter—as a practical framework. We highlight how bottlenecks shift from cellular sinks to in vivo delivery limits, offering design strategies for reliable
Junhyeong Yim, Junyoung Park, Youngjun Lee, Jongmin Park   +3 more
wiley   +1 more source

Cyclen Tetra‐Amide Ligands as a Privileged Class of Ligands for Studying Second‐Sphere Coordination Environments

Chemistry – A European Journal, EarlyView.
Cyclen tetra‐amide derivatives provide a privileged ligand platform for controlling second‐coordination sphere structure. Hydrogen‐bond networks in the second‐coordination sphere are leveraged to stabilize a EuII‐containing cyclen tetra‐amide derivative in physiologically relevant conditions by limiting the access of O2, establishing a design‐principle
Andrea L. Batchev, Widana Kaushalya, Chashitha Padukka, Janya Subasinghe, Alice R. Walker, Matthew J. Allen   +5 more
wiley   +1 more source

Assessment of Small Bowel Motility Using Cine-magnetic Resonance Imaging in Patients Suspected With Chronic Intestinal Pseudo-obstruction. [PDF]

J Neurogastroenterol Motil
Bae JH, Jung KW, Park JB, Kim K, Hong SW, Hwang SW, Park SH, Yang DH, Ye BD, Byeon JS, Yang SK, Kim MH, Kim DW, Park SH, Lee JL, Yoon YS, Kim CW, Yu CS, Myung SJ.   +18 more
europepmc   +1 more source

Titanium‐Catalyzed Diastereoselective Keto‐ and Iminonitrile Cyclizations

Chemistry – A European Journal, EarlyView.
The titanium(III)‐catalyzed diastereoselective cyclization of readily‐available substituted ketonitriles gives cyclopentanones in good yield and stereoselectivity. Subsequent 1,2‐addition allows the preparation of cyclopentyls with three consecutive stereocenters.
Christoph Kern, Ritu Singh, Michael A. Unkrig‐Bau, Lukas Jakob, Jan Streuff   +4 more
wiley   +1 more source

Innovative Management of Aerophagia-Induced Intestinal Pseudo-Obstruction in an Adult With Severe Intellectual Disability: A Case Report. [PDF]

Cureus
Yamada SM, Terada S, Harada T, Nehashi Y, Mori N.   +4 more
europepmc   +1 more source

Carbon monoxide adsorption on NaY zeolite and impregnated with 5% niobium: Characteristics and fixed‐bed study

The Canadian Journal of Chemical Engineering, EarlyView.
Schematic of the CO adsorption process in a fixed‐bed column containing pure NaY zeolite and Nb‐modified NaY (NaY–5%Nb). On the left, breakthrough curves and temperature profiles highlight the dynamic performance and thermal effects during CO adsorption.
Elson Oliveira, Karina Querne de Carvalho, Erika Pereira Felix, Roberta C. P. Rizzo‐Domingues   +3 more
wiley   +1 more source

Subtotal colectomy with ileorectal anastomosis (SCIRA) in pediatric intestinal pseudo-obstruction (PIPO): a viable option for patients with frequent enterostomy-related complications? [PDF]

Pediatr Surg Int
Petersen AE, Tabbers M, Benninga MA, Derikx JPM, Gorter RR, de Jong JR.   +5 more
europepmc   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source