Results 21 to 30 of about 10,784 (245)
Intestinal pseudo-obstruction is considered to be one of the most frequent gastrointestinal manifestations of myasthenia gravis, accompanied by the presence of neoplasia of the thymus gland in the vast majority of the cases presented in the international
Charalampos Seretis +7 more
doaj +1 more source
Challenges in management and prognosis of pediatric intestinal pseudo-obstruction
Background/Aims: Pediatric intestinal pseudo-obstruction (PIPO) is the most severe form of intestinal dysmotility in children. The aim of the study is to present the cases with PIPO in order to discuss the diagnosis, management and prognosis of PIPO ...
Özlem Boybeyi Türer +5 more
doaj +1 more source
A case of visceral myopathy with ATCG2 gene mutation misdiagnosed as Hirschsprung disease [PDF]
Objective To discuss the clinical features, differential diagnosis and complication treatment of a patient with genetic visceral myopathy. Methods Medical history, physical examination and laboratory results of the patient were collected in detail.
LIU Yuhao, ZHANG Yueyi, BAI Xiaoyin, CHEN Yang, ZHOU Weixun, LI Xiaoqing
doaj +1 more source
Autoimmune intestinal leiomyositis as a rare cause of chronic intestinal pseudo-obstruction in children: Case report with literature review [PDF]
Introduction. Chronic intestinal pseudo-obstruction represents a group of rare disorders characterized by impaired gastrointestinal motility in the absence of mechanical bowel obstruction.
Milovanović Ivan D. +4 more
doaj +1 more source
Chronic intestinal pseudo-obstruction: An unusual presentation
Chronic intestinal pseudo-obstruction (CIPO) is char- acterized by impaired gastrointestinal propulsion with signs of bowel obstruction in the absence of organic, systemic, or metabolic disorder (1).
Osama Siddique +3 more
doaj +1 more source
Functional Aerophagia in Children: A Frequent, Atypical Disorder
Aerophagia is a functional gastrointestinal disorder characterized by repetitive air swallowing, abdominal distension, belching and flatulence. Pathologic aerophagia is a condition caused by the swallowing of excessive volumes of air with associated ...
Giuliana Morabito +2 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich +35 more
wiley +1 more source
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source

