Results 21 to 30 of about 48,398 (215)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Long-term Outcome After Nonvascularized Rectus Fascia Transplantation in Solid Organ Transplantation: A Global Multicenter IIRTA Survey

Transplantation Direct
Background. Abdominal wall (AW) closure after solid organ transplantation (SOT) is challenging in case of loss of abdominal domain and/or large-for-size grafts. Primary closure is crucial to avoid open abdomen-associated morbidity and mortality.
Nele Van De Winkel, MD, Ewout Muylle, BSc, Emilio Canovai, MD, PhD, Irum Amin, MD, Andrew Butler, MD, PhD, Rodrigo Vianna, MD, Gennaro Selvaggi, MD, Pablo Farinelli, MD, Gabriel Gondolesi, MD, Carmelo Loinaz, MD, PhD, Iago Justo, MD, PhD, Hector Vilca-Melendez, MD, Ulrika Skogsberg Dahlgren, MD, Gustaf Herlenius, MD, PhD, Alireza Shamsaeefar, MD, Hamed Nikoupour, MD, Antoine Dubois, MD, Marc Miserez, MD, PhD, André D’Hoore, MD, PhD, Robert Venick, MD, Jacques Pirenne, MD, PhD, Laurens J. Ceulemans, MD, PhD   +21 more
doaj   +1 more source

Bridging Liver Transplantation in the Treatment of Intestinal Failure Associated Liver Disease in Infants—A Bridge Too Far?

Children, 2022
Infants with intestinal failure associated liver disease (IFALD) requiring liver and bowel transplant have a high mortality on the transplant waiting list due to the scarcity of the size-matched donor organs.
Abubakar Sharif, Khalid Sharif, Darius F. Mirza, Girish L. Gupte   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Massive bowel resection for children with non-short bowel syndrome intestinal failure

Intestinal Failure
Introduction: Pediatric patients with chronic intestinal pseudo-obstruction (CIPO) and congenital diarrheas and enteropathies (CODE) are unique intestinal failure (IF) patient populations.
FY Takamatsu, P. Wales, C. Belza, E. Garofalo, S. Wong-Sterling, D. Yanchis, G. Courtney-Martin, Y. Avitzur   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Simultaneous Intestinal and Kidney Transplantation in Adults

Journal of Investigative Surgery, 2019
Aim of the study: Intestinal transplantation (IT) is a life-saving procedure for carefully selected patients with intestinal failure. We evaluated patients who had undergone simultaneous intestinal and kidney transplantation (SIKT) to determine whether ...
Irum Amin, Charlotte Rutter, Adam Barlow, Neil K. Russell, J. Andrew Bradley, Andrew Jackson, Andrew J. Butler   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Impact of plasma aluminum on neurocognitive outcomes at early school age in children with intestinal failure

Intestinal Failure
Background: Aluminum (AL) is a known contaminant in parenteral nutrition (PN) and is associated with bone disease, and neurotoxicity. We aimed to evaluate the association between plasma AL concentration and neurocognitive outcomes at early school age, in
Camille Maltais-Bilodeau, Rivka Green, Glenda Courtney-Martin, Daniela Gattini, Christina Belza, Anna Gold, Yaron Avitzur   +6 more
doaj   +1 more source