Results 111 to 120 of about 381,707 (285)

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Comparison of microbiota in different intestinal regions between hibernating and active Daurian ground squirrels

The European Zoological Journal
The gut microbiota plays a crucial role in modulating host physiology and behaviour. While seasonal variations in gut microbiota have been extensively documented, microbial adaptations across distinct intestinal regions during hibernation and active ...
Y. H. Zheng, X. K. Lin, X. Y. Pan, X. M. Ma, X. Y. Ju, J. L. Wang   +5 more
doaj   +1 more source

Decreased number of mature goblet cells in the large intestine of adult Oasis−/− mice.

, 2014
(A) Peptide features of mouse OASIS and ATF6. (B) RT-PCR analysis of Oasis mRNA in various tissues from 8-week-old mice. Oasis mRNA was highly expressed in the large intestine.
Kazunori Imaizumi (278083), Rie Asada (278078), Soshi Kanemoto (278076), Kenta Hino (519150), Atsushi Saito (278077)   +4 more
core   +1 more source

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

Analyzing the functionality of the human intestinal microbiota by stable isotope probing

, 2010
Key words: gut bacteria, dietary carbohydrates, digestion, RNA-SIP, TIM-2, HITChip, human trial The human gastro-intestinal (GI) tract comprises a series of complex and dynamic organs ranging from the stomach to the distal colon, which harbor immense ...
Kovatcheva, P.P.
core  

Limited ablation of p120 in the small and large Intestine.

, 2013
At the two-month time point sections of the small (A) and large (B) intestine were co-stained with p120 (i and iv) and E-cadherin (ii and v). Arrows indicate regions of p120 KO.
Peilin Jia (36888), Zhongming Zhao (40519), Sylvie Robine (351514), M. Kay Washington (178897), Andrey Efimov (351510), Albert B. Reynolds (111905), Sarah P. Short (111880), Whitney G. Smalley-Freed (351508), Robert J. Coffey (225448)   +8 more
core   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Increasing digesta viscosity may increase parasite establishment in the small intestine of sheep

, 2005
Strongyle infections and diarrhoea are major problems for the sheep industry, but the nutritional factors determining faecal consistency and susceptibility to enteric diseases are not well understood.
Pluske, J.R., Besier, R.B., Pethick, D.W., Bath-Jacobson, C.L., Bell, K.   +4 more
core  

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source