E-cadherin can limit the transforming properties of activating β-catenin mutations [PDF]
Wnt pathway deregulation is a common characteristic of many cancers. But only Colorectal Cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of pancreas) have activating ...
Alan R Clarke +27 more
core +2 more sources
Feed interventions and skatole deposition [PDF]
Skatole produced in the large intestine of the pig and the testicular steroid androstenone are the main substances contributing to boar tainted meat from entire male pigs.
Jensen, Rikke Lassen
core
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Effect of nipasol on composition of luminal microflora in large intestine of white rats
The effect of the antimicrobial preservative nipasol on qualitative and quantitative composition of large intestine microflora in rats was studied. It was established that representatives of genera Bacteroides, Bifidobacterium, Lactobacillus, Escherichia,
N. Skochylyas, Ya. Kolisnyk
doaj +1 more source
To respond or not to respond - a personal perspective of intestinal tolerance [PDF]
For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka +142 more
core +1 more source
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
The Lumenal Microbiota Varies Biogeographically in the Gastrointestinal Tract of Rhesus Macaques
The strategy of adjusting the composition of gastrointestinal microbiota has shown great promise for the treatment of diseases. Currently, the relationship between gut microbes and human diseases is mainly presented by the fecal microbiota from the colon.
Yaping Yan +4 more
doaj +1 more source
Deep-sea nematodes (Comesomatidae) from the Southwest Pacific Ocean: five new species and three new species records [PDF]
The present study describes five new free-living nematode species and provides three new species records of the family Comesomatidae (genera Cervonema Wieser, 1954, Dorylaimopsis Ditlevsen, 1918, Hopperia Vitiello, 1969, and Kenyanema Muthumbi et al ...
Leduc, Daniel
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Pigs experimentally infected with Serpulina hyodysenteriae can be protected from developing swine dysentery by feeding them a highly digestible diet [PDF]
Weaner pigs (n = 72) were fed 1 of 4 diets. These were based on either cooked rice and animal protein, cooked rice and lupin, wheat and lupin, or wheat and animal protein. Twenty-six of the pigs were slaughtered after 1 month.
Siba, P.M., Pethick, D.W., Hampson, D.J.
core +2 more sources

