Results 211 to 220 of about 689,502 (309)

Trichobezoar-associated jejunojejunal intussusception: an exceptionally rare manifestation of Rapunzel syndrome. [PDF]

J Surg Case Rep
Vyas S, Sharma H.
europepmc   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

LRRK2^R1627P mutation amplifies environmental risk factors induced chronic inflammation and α-synuclein aggregation in the gut of rats. [PDF]

NPJ Parkinsons Dis
Pang S, Lu J, Wang Y, Ying C, Zhao C, Yue Z, Yang Q, Chan P.   +7 more
europepmc   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Integrated morphological, molecular, and immunopathological characterization of Raillietina hymenolepidoides from Psammomys obesus reveals potent in vitro anthelmintic activity of Androctonus crassicauda venom. [PDF]

Sci Rep
Anwar FAS, Alkenani NA, Abd-Elghaffar SK, Omar HEM, Abdel-Maksoud FM, Abdelsater N, Mohamed ISE, Rudayni H, Al-Zharani M, Dossouvi KM, Elkelish A, Mohamed SAA.   +11 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

KIT supports small intestinal tuft cell hyperplasia. [PDF]

Sci Adv
Lara HI, Bell MR, O'Connor S, Ting HA, von Moltke J.   +4 more
europepmc   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Small Bowel Obstruction Associated With a Mesenteric Lymphatic Malformation: A Case Report. [PDF]

Cureus
Shinoda M, Inose S, Ito H, Kanai N, Kurihara K.   +4 more
europepmc   +1 more source