Results 251 to 260 of about 5,699,404 (283)

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Peyer's patch M cells organize an epithelial niche that sustains group 3 innate lymphoid cells and IL-22. [PDF]

Nat Immunol
Cao WHJ, You Y, Wang N, Chaudhry MZ, Yu H, Bell PT, Noye EC, Denman R, Lee B, Waddington A, Ye J, Schreuder J, Huang Q, Tellier J, Curio S, Santiago J, Amann-Zalcenstein D, Jacquelot N, Hickey P, Nutt SL, Seillet C, Hansbro PM, Wimmer VC, Strugnell RA, Tuong ZK, Ritchie ME, Belz GT.   +26 more
europepmc   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

Advanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto, Emily Tsang, Marie Karen Tracy Hong Lin, Luca Mannino, Kurt V. Gothelf, Anja Boisen   +5 more
wiley   +1 more source

Effect of ischemic preconditioning on the expression of Cx43 protein in intestinal ischemia-reperfusion injury in SD rats. [PDF]

Front Physiol
Liu N, Ma Y, Han Z, Zhang Q, Cao J.
europepmc   +1 more source

<i>Saccharomyces boulardii</i> CNCM I-745 protects against small intestinal injury in a model of gliadin-peptide-induced sterile inflammatory enteropathy. [PDF]

Front Immunol
Lezcano A, Miculan E, Ducca G, Ruera C, Iribarren ML, Tixador P, Roux X, Chirdo FG.   +7 more
europepmc   +1 more source

Bile acid sequestration reveals microbiome remodeling that dominates FXR signaling to shape host responses to enteric infection. [PDF]

PLoS Pathog
Mansouripour A, Seeger DR, Parmer M, Kotha P, Golovko AM, Golovko MY, Solaymani-Mohammadi S.   +6 more
europepmc   +1 more source

Optimized technique for experimental multivisceral transplantation. [PDF]

Intest Fail
Abate JC, Stringa P, Largo C, Vecchio L, Lausada N, Machuca M, Camps O, Sanchez-Verde Bilbao J, Hernández Oliveros F, Andrés Moreno AM.   +9 more
europepmc   +1 more source

Intestinal microbiota in nursery pigs: comments on anatomical location, spatial niches, and approaches to data interpretation. [PDF]

Microbiome Res Rep
Gormley AR, Garavito-Duarte Y, Son J, Kim SW.   +3 more
europepmc   +1 more source

NLRP6 as a candidate segmental barrier to carcinogenesis in the human gut: a hypothesis. [PDF]

Front Immunol
Luengo-Gil G, Arroyo AB, Hurtado-López AM, García-Solano J, Conesa-Zamora P, Tapia-Abellán A.   +5 more
europepmc   +1 more source