Results 21 to 30 of about 842,489 (314)
Viable bacterial colonization is highly limited in the human intestine in utero
Nature Medicine, 2020 Mucosal immunity develops in the human fetal intestine by 11–14 weeks of gestation, yet whether viable microbes exist in utero and interact with the intestinal immune system is unknown.
E. Rackaityte +8 more
semanticscholar +1 more source
Intestinal parasites: Associations with intestinal and systemic inflammation [PDF]
Parasite Immunology, 2018 SummaryThe aim of the present study was to evaluate associations between intestinal parasitic infection with intestinal and systemic inflammatory markers in school‐aged children with high rates of obesity. Plasma concentrations of C‐Reactive Protein (CRP), leptin, TNF‐α, IL‐6 and IL‐10 were measured as systemic inflammation markers and count of stool ...
G. A. Zavala +7 more
openaire +2 more sources
Zhongliu Fangzhi Yanjiu, 2023 Objective To investigate the effect of GHET1 on the biological behavior of gallbladder cancer cells and the regulatory mechanism of GHET1 on miR-27b. Methods The expression of GHET1 and miR-27b in 50 samples of gallbladder cancer was detected by real ...
YANG Zhen, LI Wenchuan, ZHOU Ning
doaj +1 more source
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
Scientific Reports, 2018 Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated,
Magdalena Kasendra +12 more
semanticscholar +1 more source
The Paneth Cell: The Curator and Defender of the Immature Small Intestine
Frontiers in Immunology, 2020 Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their cytoplasm.
Shiloh R Lueschow, Steven J. Mcelroy
semanticscholar +1 more source
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model
eLife, 2020 Induction of intestinal drug metabolizing enzymes can complicate the development of new drugs, owing to the potential to cause drug-drug interactions (DDIs) leading to changes in pharmacokinetics, safety and efficacy.
Magdalena Kasendra +13 more
semanticscholar +1 more source
Frontiers in Medicine, 2022 Methamphetamine (METH) is an illegal drug widely abused in many countries. Methamphetamine abuse is a major health and social problem all over the world. However, the effects of METH on the digestive system have rarely been reported. Previous studies and
Yuansen Li +8 more
doaj +1 more source
Intestinal spirochaetosis [PDF]
Gut, 1971 An abnormal condition of the large intestine is described in which the surface epithelium is infested by short spirochaetes. Diagnosis can be made by light microscopy. A review of 14 cases diagnosed by rectal biopsy and 62 cases involving the appendix shows no consistent symptom complex. The possible significance is discussed.
F D, Lee +5 more
openaire +2 more sources
N6-Methyladenosine Regulators Promote Malignant Progression of Gastric Adenocarcinoma
Frontiers in Oncology, 2022 N6-methyladenosine (m6A) RNA methylation is dynamically and reversibly regulated by methyltransferases, binding proteins, and demethylases. The restoration of m6A to adenosine could result in demethylation modifications.
Yibin Zhao +4 more
doaj +1 more source