Results 31 to 40 of about 842,489 (314)

The gut, the bad and the harmless: Candida albicans as a commensal and opportunistic pathogen in the intestine

Current Opinion in Microbiology, 2020
Summary Candida albicans is a regular member of the intestinal microbiota in the majority of the human population. This underscores C. albicans’ adaptation to life in the intestine without inducing competitive interactions with other microbes or immune ...
C. Kumamoto, M. Gresnigt, B. Hube
semanticscholar   +1 more source

Long noncoding RNA TUG1 regulates the progression of colorectal cancer through miR-542-3p/TRIB2 axis and Wnt/β-catenin pathway

Diagnostic Pathology, 2021
Background Colorectal cancer (CRC) is one of the third normal malignancy worldwide. Taurine-upregulated gene 1 (TUG1), a member of long noncoding RNAs (lncRNAs), has been reported to be involved in various cancers.
Quanlin Liu, Wei Zhang, Linshan Luo, Keshun Han, Ruitao Liu, Shue Wei, Xiaoran Guo   +6 more
doaj   +1 more source

Ageing, metabolism and the intestine

EMBO Reports, 2020
The intestinal epithelium serves as a dynamic barrier to the environment and integrates a variety of signals, including those from metabolites, commensal microbiota, immune responses and stressors upon ageing.
Maja C. Funk, Jun Zhou, M. Boutros
semanticscholar   +1 more source

Residual cancer is a strong predictor of survival in T3 incidental gallbladder cancer

BMC Surgery, 2022
Background and purpose Index cholecystectomy is insufficient for curing T3 incidental gallbladder cancer (IGC), and once residual cancer (RC) is found, the prognosis is often poor.
Chuan You, Mengyi Xie, Meng Ling, Facai Yang, Yinghe Qiu, Jingdong Li   +5 more
doaj   +1 more source

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine

Journal of Experimental Medicine, 2019
Single-cell transcriptome analysis of epithelial cells from human ileum, colon, and rectum reveals different nutrient-absorption preferences in the small and large intestine, providing a rich resource for further characterization of human intestine cell ...
Yalong Wang, Wanlu Song, Jilian Wang, Ting Wang, X. Xiong, Zhen Qi, W. Fu, Xuerui Yang, Ye-Guang Chen   +8 more
semanticscholar   +1 more source

The role of radiotherapy for patients with primary tracheal carcinoma: two case reports of tracheal carina squamous cell carcinoma and literature review

Frontiers in Oncology
Primary tracheal carcinoma is a rare malignant tumor; its optimal treatment strategy is not yet formally proven. Surgery, especially complete surgical excision, is often considered as the first-line treatment, and chemotherapy has been reported ...
Xiaojing Chang, Xiaojing Chang, Zhesen Tian, Yalei Zhao, Xiaohui Ge, Feng Li, Yu Yang, Huizhi Liu   +7 more
doaj   +1 more source

Identification of Circ_001569 as a Potential Biomarker in the Diagnosis and Prognosis of Pancreatic Cancer

Technology in Cancer Research & Treatment, 2021
Emerging evidence has shown that circular RNAs (circRNAs) serve as a promising biomarker in different malignancies. Specifically, circ_001569 has been found to be upregulated in some types of human gastrointestinal cancer.
Xianbo Shen MM, Yun Chen BS, Jibin Li BS, Huaiyin Huang MM, Chuping Liu MM, Ning Zhou MD   +5 more
doaj   +1 more source

lncRNA LINC00460 Silencing Represses EMT in Colon Cancer through Downregulation of ANXA2 via Upregulating miR-433-3p

Molecular Therapy: Nucleic Acids, 2020
Colon cancer (CC), one of the major causes of tumor-associated death, is often presented with a heterogenic pool of cells with unique differentiation patterns. This study explored the functions that LINC00460 displayed in CC by regulating microRNA-433-3p
Weiwen Hong, Hongan Ying, Feng Lin, Ruliang Ding, Weiya Wang, Meng Zhang   +5 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Tectorigenin inhibits Caco-2 human colon cells via NF-κB pathway suppression

Bangladesh Journal of Pharmacology, 2015
Effective immunomodulator and pro-inflammatory cytokine, Tumor necrosis factor-α (TNF-α) are considered to be responsible for connecting autoimmune pathological process and contagious diseases.
Xiao-Yu Dai, Yong-Ming Yu, Zheng-Fang Kong, Yi-Sheng Cao, Dan-Dan Huang, Xiao-Rong Hu, Zuo-An Huang, Yang-Yang Xie, Shun Zhang   +8 more
doaj   +1 more source