Results 91 to 100 of about 260,280 (288)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
THE INTESTINAL MICROBIOTA IN RAINBOW TROUT (ONCORHYNCHUS MYKISS) IS INFLUENCED BY DIET TYPE AND YERSINIA RUCKERI CHALLENGE [PDF]
, 2013 In recent years it has become more and more evident that the bacterial flora in the gut of warm-blooded animals modulates physiological processes and the immunological status of the host.
Dalsgaard, Inger +3 more
core
Feeding with chicory roots reduces the amount of odorous compounds in colon and rectal contents of pigs [PDF]
, 2006 Sixteen pigs (eight entire males and eight females) were given individually two diets, control and control added 25% chopped chicory roots for 2 months before slaughter.
Hansen, L.L., Jensen, M.T.
core +1 more source
Biochemical Journal, 2004 In this issue of the Biochemical Journal, Robbe et al. have employed a state-of-the-art MS technique to re-examine the sweet and sticky sugar covering of human intestinal mucosa. The availability of highly sensitive MS methods has been instrumental in determining the complex structures of mucin oligosaccharides, and in demonstrating that there are ...
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Atresia of ileocecal junction, ileocecal valve: Rare variants of bowel atresia
Journal of Indian Association of Pediatric Surgeons, 2009 Atresia of ileocecal junction and isolated atresia of ileocecal valve are rare types of intestinal atresia with very few reports in literature. We report two such cases. Radiology showed dilated ileal segment and distal micro colon in both the cases.
Srivastava Punit +6 more
doaj
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Accuracy of Plain Digital Radiography for the Detection of Gastrointestinal Masses in Dogs and Cats
AnimalsAbdominal radiography is commonly used as an initial diagnostic tool in dogs and cats with gastrointestinal (GI) signs. Historically, abdominal radiographs were considered unreliable for detecting GI masses, with detection rates below 50%. The purpose of
Keaton Cortez +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Біологічні студії, 2017 Сonjugates of antisense ODN (asODN) with three newly synthesized samples (MP-2, MP-2, MP-27) of polymer carriers based on DMAEM have been studied. It was found that these best conjugates could be created by mixing 0.5 % solution of polymers with asODN ...
N. U. Susol
doaj +1 more source