Results 61 to 70 of about 25,379 (250)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Arterial supply of the intestines of New Zealand rabbits (Oryctolagus cuniculus) [PDF]

open access: yesBiotemas, 2008
The origin and ramification patterns of the intestinal arteries of rabbits were studied. The vessels were injected with a latex solution before dissection in 20 adult specimens.
Leandro Marcel Fernandes Cortellini   +4 more
doaj  

USE OF THE ENROFLOXACIN IN BEEKEEPING

open access: yesВетеринарная патология, 2020
The aim of the study was to study the effect of a broad-spectrum antibiotic - enrofloxacin on the qualitative and quantitative composition of the intestinal microflora of honey bees.
I. V. Serdyuchenko   +4 more
doaj   +1 more source

Association between overall dietary quality and constipation in American adults: a cross-sectional study

open access: yesBMC Public Health, 2022
Background Constipation seriously affects people’s life quality, and dietary adjustment has been one of the effective methods. Overall dietary quality has been reported to be associated with some diseases, while its association with constipation has not ...
Qingye Liu, Yulong Kang, Jin Yan
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Pitfalls in ultrasound imaging of the stomach and the intestines

open access: yesJournal of Ultrasonography, 2018
The gastrointestinal tract is an extraordinary human organ in terms of its morphology and function. Its complex structure and enormous length as well as frequent presence of gas discourage many doctors performing ultrasound examination from its ...
Andrzej Smereczyński   +1 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Histomorphology of PAF stimulated intestines pretreated with dexamethasone or quinidine.

open access: yes, 2015
PAS-stained sections of longitudinal intestinal slices. A. Fluid accumulations at the villus tips (arrows) of PAF-stimulated intestines after pretreatment with dexamethasone (n = 1); B.
Jürgen Sarau (706817)   +8 more
core   +1 more source

Effects of Epidermal Growth Factor on Neonatal Growth of Rat Intestines [PDF]

open access: yes, 1994
The effects of epidermal growth factor (EGF) on neonatal intestines were examined in the rat. In 5-day-old rats, sucrase, trehalase, alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (gamma-GTP) activities in the small intestines were ...
Eguchi, Katsuto   +3 more
core   +1 more source

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