Results 71 to 80 of about 260,280 (288)

Arterial supply of the intestines of New Zealand rabbits (Oryctolagus cuniculus) [PDF]

open access: yesBiotemas, 2008
The origin and ramification patterns of the intestinal arteries of rabbits were studied. The vessels were injected with a latex solution before dissection in 20 adult specimens.
Leandro Marcel Fernandes Cortellini   +4 more
doaj  

Immunomodulatory effects of probiotics

open access: yesМедицинский совет, 2020
Today, there is an explosion of discoveries related to a growing understanding of the role of microbial communities, key species of bacteria, products or metabolites derived from commensals, and in particular the relationship between some of these ...
E. Yu. Plotnikova, Yu. V. Zakharova
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Association between overall dietary quality and constipation in American adults: a cross-sectional study

open access: yesBMC Public Health, 2022
Background Constipation seriously affects people’s life quality, and dietary adjustment has been one of the effective methods. Overall dietary quality has been reported to be associated with some diseases, while its association with constipation has not ...
Qingye Liu, Yulong Kang, Jin Yan
doaj   +1 more source

Sacrifice and business : a comparative study of ritual and commercial cattle slaughtering in Tenkodogo, Burkina Faso [PDF]

open access: yes, 2006
All over the world meat plays an important role in the nutrition of people. Mostly it is considered to be a special source of strength and health. In many peoples' minds the consumption of animal products, such as muscle, fat, blood, inner organs and ...
Zimmermann, Hans
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

USE OF THE ENROFLOXACIN IN BEEKEEPING

open access: yesВетеринарная патология, 2020
The aim of the study was to study the effect of a broad-spectrum antibiotic - enrofloxacin on the qualitative and quantitative composition of the intestinal microflora of honey bees.
I. V. Serdyuchenko   +4 more
doaj   +1 more source

A case of histoplasmosis Report 1. Cinical, mycological and pathological observations [PDF]

open access: yes, 1957
In our country it has been believed that there is no histoplasmosis here in Japan. However, from the above clinical signs, radiological characteristics, laboratory tests, pathological and mycological examinations, and experimental findings, we believe ...
Hamazaki, Yukio   +6 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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