Results 61 to 70 of about 89,298 (288)

A new perspective on metformin therapy in type 1 diabetes [PDF]

, 2017
Metformin is quite frequently used off-label in type 1 diabetes to limit insulin dose requirement. Guidelines recommend that it can improve glucose control in those who are overweight and obese but evidence in support of this is limited.
Boyle, James G., Livingstone, Rachel, Petrie, John R.   +2 more
core   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

Rough Set Based Approach for IMT Automatic Estimation [PDF]

, 2012
Carotid artery (CA) intima-media thickness (IMT) is commonly deemed as one of the risk marker for cardiovascular diseases. The automatic estimation of the IMT on ultrasound images is based on the correct identification of the lumen-intima (LI) and media ...
Balestra, Gabriella, Molinari, Filippo, Rosati, Samanta   +2 more
core  

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Long-term use of first-line highly active antiretroviral therapy is not associated with carotid artery stiffness in human immunodeficiency virus-positive patients

Brazilian Journal of Infectious Diseases, 2014
Objective: To evaluate whether or not highly active antiretroviral therapy is associated with carotid artery stiffness in human immunodeficiency virus-positive patients in Henan Province, China.
Haohui Zhu, Jianjun Yuan, Yisa Wang, Fan Gao, Xiao Wang, Changhua Wei, Jiyun Chen, Xiaohui Fan, Mei Zhang   +8 more
doaj   +1 more source

Effects of smoking and cessation on subclinical arterial disease: a substudy of a randomized controlled trial. [PDF]

PLoS ONE, 2012
The mechanisms by which smoking cessation reduces cardiovascular disease risk are unclear. We evaluated longitudinal changes in carotid intima-media thickness among current smokers enrolled in a prospective, randomized smoking cessation clinical trial ...
Heather M Johnson, Megan E Piper, Timothy B Baker, Michael C Fiore, James H Stein   +4 more
doaj   +1 more source

Immune-mediated inflammation promotes subclinical atherosclerosis in recent-onset psoriatic arthritis patients without conventional cardiovascular risk factors [PDF]

, 2018
Studies on the inflammatory burden in recent-onset psoriatic arthritis (PsA) patients without conventional cardiovascular risk factors (CVRFs) are not available.
Capani, Francisco, Chiocconi, Monica, Cosentino, Vanesa Laura, Kerzberg, Eduardo Mario, Kogan, Nora, Kolliker Frers, Rodolfo Alberto, Otero-Losada, Matilde Estela, Tau, Julia, Urdapilleta, Adriana   +8 more
core   +1 more source

Heritability of carotid intima-media thickness: A twin study [PDF]

Atherosclerosis, 2008
To estimate the heritability of carotid intima-media thickness (IMT), a surrogate marker for atherosclerosis, independent of traditional coronary risk factors.We performed a classical twin study of carotid IMT using 98 middle-aged male twin pairs, 58 monozygotic (MZ) and 40 dizygotic (DZ) pairs, from the Vietnam Era Twin Registry.
Zhao, Jinying, Cheema, Faiz A., Bremner, J. Douglas, Goldberg, Jack, Su, Shaoyong, Snieder, Harold, Maisano, Carisa, Jones, Linda, Javed, Farhan, Murrah, Nancy, Le, Ngoc-Anh, Vaccarino, Viola   +11 more
openaire   +3 more sources

Targeting the Mapk13‐Tcf1‐Slc7a5 Axis via One‐Carbon Metabolic Regulation to Prevent Chronic Allograft Vasculopathy

Advanced Science, EarlyView.
This study emphasizes the role of the Mapk13‐Tcf1‐Slc7a5‐methionine metabolism axis in stem‐like CD4+ T cells. Moreover, it uncovers the mechanism through which limiting one‐carbon metabolism in CD4+ stem‐like T cells suppresses the tide of chronic allograft vasculopathy, offering potential targets to promote long‐term graft survival.
Wang Yi, Di Wu, Jing Liu, Shi Chen, Liu Song, Bin Xie, Aini Xie, Peixiang Lan, Zhishui Chen   +8 more
wiley   +1 more source

Intima–media complex thickness and carotid atherosclerotic plaque formation in Lublin’s population in the context of selected comorbidities

Journal of Ultrasonography, 2018
Introduction: Atherosclerosis (arteriosclerosis) is a chronic arterial disease of the arteries with chronic inflammatory. The pathology of atherosclerosis is complex, and the atherosclerotic process is multi-factorial, not fully understood.
Tomasz Słomka, Anna Drelich-Zbroja, Magdalena Jarząbek, Małgorzata Szczerbo-Trojanowska   +3 more
doaj   +1 more source