Results 51 to 60 of about 595,091 (292)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The psychopathic intimate partner batterer: a non-psychopathological profile

Anales de Psicologia, 2014
This theoretical study reviews two of the most cited profiles of intimate partner batterers in the scientific literature, paying special attention to the most notable differences between them, as well as to their common criteria. The study also discusses
José M. Pozueco-Romero, Juan M. Moreno-Manso, Macarena Blázquez-Alonso, María E. García-Baamonde   +3 more
doaj   +1 more source

Ending violence against women: Help-seeking behaviour of women exposed to intimate partner violence in sub-Saharan Africa.

PLoS ONE, 2023
IntroductionIntimate partner violence is a serious public health problem that transcends cultural boundaries in sub-Saharan Africa. Studies have reported that violence characteristics and perception are strong predictors of help-seeking among women.
Richard Gyan Aboagye, Abdul-Aziz Seidu, Abdul Cadri, Tarif Salihu, Francis Arthur-Holmes, Sarah Tara Sam, Bright Opoku Ahinkorah   +6 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Intimate partner violence during pregnancy in the Northern Iran (2010)

مجله دانشگاه علوم پزشکی گرگان, 2015
Background and Objective: Pregnancy can not only protect mothers against intimate partner violence but even it may increase the rate and severity of intimate partner violence.
Abdollahi F, Yazdani - Cherati J, Majidi Z   +2 more
doaj  

Intimate Partner Violence During Pregnancy and Maternal Morbidity in South Ethiopia: A Cohort Study

Journal of Multidisciplinary Healthcare, 2023
Mesfin Mamo Utaile,1,2 Ahmed Ali Ahmed,2 Alemayehu Worku Yalew2 1Department of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia; 2Department of Preventive Medicine, School of Public Health, College of ...
Utaile MM, Ahmed AA, Yalew AW
doaj  

Assessing the implications of women's economic status on intimate partner violence in Dar es Salaam and Mbeya, Tanzania. [PDF]

Sociological and economic bargaining theories have different predictions on how women's economic status - primarily women's employment - affects their risk of partner violence.
Vyas, Seema
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Impact of partner alcohol use on intimate partner violence among reproductive-age women in East Africa Demographic and Health Survey: propensity score matching

BMC Public Health
Introduction Intimate Partner Violence (IPV) is the most prevalent form of violence against women globally and is more prevalent than rape or other violent attacks by strangers.
Mamaru Melkam, Bezawit Melak Fente, Yohannes Mekuria Negussie, Zufan Alamrie Asmare, Hiwot Altaye Asebe, Beminate Lemma Seifu, Meklit Melaku Bezie, Angwach Abrham Asnake   +7 more
doaj   +1 more source