Results 81 to 90 of about 650,139 (297)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Cash transfers and intimate partner violence: What does the evidence say?

, 2019
Cash transfers are a popular tool to address poverty and food insecurity, but can they also reduce women’s risk of intimate partner violence?Non-PRIFPRI1; G Cross-cutting gender theme; CRP2; Cash Transfer and Intimate Partner Violence Research ...
Cash Transfer and Intimate Partner Violence Research Collaborative
core  

Breaking apart intimate partner violence and abuse /

, 2023
"Breaking Apart Intimate Partner Violence and Abuse provides a thorough examination of intimate partner violence and abuse, encompassing the nature, incurring factors, and the impact of its presence in interpersonal relationships"-
Nash, Shondrah Tarrezz,, Geurin, Lynn,, Shannon, Lisa Michele,, Himes, Monica,   +3 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Socioeconomic inequalities in victims of intimate partner violence in Europe

, 2013
Costa D, Soares J, Lindert J, et al. Socioeconomic inequalities in victims of intimate partner violence in Europe. European Journal of Public Health. 2013;23(Suppl.
Soares, J, Degomme, O., Barros, H., Degomme, O, Hatzidimitriadou, E, Soares, J., Lindert, J, Ioannidi-Kapolo, E, Hatzidimitriadou, E., Sundin, O., Barros, H, Costa, D., Ioannidi-Kapolou, E, Cervilla, J, Ioannidi-Kapolou, E., Toth, O, Costa, Diogo ; https://orcid.org/, Costa, D, Toth, O., Lindert, J., Sundin, O, Cervilla, J.   +21 more
core   +1 more source

Perception of Beninese on intimate partner violence: evidence from 2011-2012 Benin demographic health survey

BMC Women's Health, 2018
Background Violence against women remains an important issue of inequality in African societies, with several consequences to health, social and economic status.
Alphonse Kpozehouen, Noël Moussiliou Paraïso, Yolaine Glèlè Ahanhanzo, Elvyre Klikpo, Charles Sossa Jérôme, Laurent T. Ouédraogo, Roger Salamon   +6 more
doaj   +1 more source

Intimate Partner Violence and Parenting

JAMA Pediatrics
This cohort study evaluates parental stress and protective factors mitigating risks for child maltreatment in the context of intimate partner violence.
Temple, Jeff R., Baumler, Elizabeth, Wood, Leila   +2 more
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source