Results 121 to 130 of about 311,206 (329)

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

What factors are associated with recent intimate partner violence? findings from the WHO multi-country study on women's health and domestic violence

BMC Public Health, 2011
BackgroundIntimate partner violence (IPV) against women is a global public health and human rights concern. Despite a growing body of research into risk factors for IPV, methodological differences limit the extent to which comparisons can be made between
T. Abramsky, C. Watts, C. Garcia-Moreno, K. Devries, L. Kiss, M. Ellsberg, H. Jansen, L. Heise   +7 more
semanticscholar   +1 more source

Intimate Partner Violence in Omaha [PDF]

, 2010
While the greater Omaha area has an extensive network of service providers addressing the needs of Intimate Partner Violence (IPV) survivors and has made great strides to increase collaboration and outreach, opportunities exist to enhance service ...
Maggie Skrypek, Monica Idzelis
core  

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source

Older Women Face Psychological and Physical Abuse [PDF]

, 2017
A shorter version of this article appeared on pp. 1–4 of the Summer 2017 print edition.This article examines psychological and physical abuse against women in Alaska who are aged 60 or older and compares these rates to national rates. Psychological abuse
Rosay, André B.
core  

Intimate partner violence during pregnancy and risks of low birth weight and preterm birth in hospitals of Tigray, Northern Ethiopia

Scientific Reports
Intimate partner Violence (IPV) can affect any woman, irrespective of their economic status, religion, or culture. This is a human-rights issue and due to its prevalence and adverse effects on pregnancy and birth, it must be given greater attention ...
Kahsay Zenebe Gebreslasie, Solomon Weldemariam, Gelawdyos Gebre, Dawit Zenebe, Mihreteab Mehari, Aklil Birhane, Rebecca Susan Dewey   +6 more
doaj   +1 more source

A social empowerment intervention to prevent intimate partner violence against women in a microfinance scheme in Tanzania: findings from the MAISHA cluster randomised controlled trial

The Lancet Global Health, 2019
Summary: Background: Globally, about 30% of women have experienced physical or sexual violence, or both, from an intimate partner during their lifetime.
Saidi Kapiga, ProfMD, Sheila Harvey, PhD, Gerry Mshana, PhD, Christian Holm Hansen, PhD, Grace J Mtolela, Flora Madaha, BA, Ramadhan Hashim, PGD, Imma Kapinga, BA, Neema Mosha, MSc, Tanya Abramsky, MSc, Shelley Lees, PhD, Charlotte Watts, ProfPhD   +11 more
doaj   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Financial inclusion and intimate partner violence: What does the evidence suggest?

PLoS ONE, 2019
Financial inclusion is an area of growing global interest in women's empowerment policy and programming. While increased economic autonomy may be expected to reduce the prevalence of intimate partner violence, the mechanisms and contexts through which ...
Lotus McDougal, Jeni Klugman, Nabamallika Dehingia, Amruta Trivedi, Anita Raj   +4 more
doaj   +1 more source

NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation

Advanced Science, EarlyView.
NIBAN2, highly expressed in glioma stem‐like cells (GSCs), assembles with FLII and transcription factor RREB1 to form a nuclear complex. This complex transcriptionally activates stemness‐associated genes (e.g., CD44, NANOG) and metabolic enzymes (e.g., LDHA), thereby sustaining both transcriptional and metabolic stemness programs.
Liang liang Shi, Xinwei Qiao, Yue Hu, Minjie Wang, Shaojie Yu, Zihan Gong, Yuxin Rao, Hui Zheng, Siting Chen, Lin Li, Rong Fu, Tao Liang, Jin Yao, Xiaobing Jiang, Junjun Li   +14 more
wiley   +1 more source