Results 71 to 80 of about 268,314 (337)

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in the State of Alaska: Key Results from the 2010 Alaska Victimization Survey [PDF]

, 2011
This document is a two-page summary of the key results from the 2010 Alaska Victimization Survey for Alaska statewide. The Alaska Victimization Survey, designed to establish a baseline for estimates of intimate partner and sexual violence, is modeled ...
Rosay, André B.
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Understanding the nature and etiology of intimate partner violence and [PDF]

, 2011
Theoretical perspectives underlying hypotheses about the nature and etiology of intimate partner violence are important as they inform professionals how they should best respond to reduce or eliminate this social problem.
Dixon, Louise
core  

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Impact of partner alcohol use on intimate partner violence among reproductive-age women in East Africa Demographic and Health Survey: propensity score matching

BMC Public Health
Introduction Intimate Partner Violence (IPV) is the most prevalent form of violence against women globally and is more prevalent than rape or other violent attacks by strangers.
Mamaru Melkam, Bezawit Melak Fente, Yohannes Mekuria Negussie, Zufan Alamrie Asmare, Hiwot Altaye Asebe, Beminate Lemma Seifu, Meklit Melaku Bezie, Angwach Abrham Asnake   +7 more
doaj   +1 more source

Exploring the complex pathway of the primary health care response to intimate partner violence in New Zealand

Health Research Policy and Systems, 2018
Background Integrating sustainable responses to intimate partner violence in health care is a persistent and complex problem internationally. New Zealand holds a leading role, having established national health system infrastructure for responding to ...
Claire Gear, Elizabeth Eppel, Jane Koziol-Mclain   +2 more
doaj   +1 more source

High rate of partner violence during pregnancy in eastern Ethiopia: Findings from a facility-based study.

PLoS ONE, 2020
INTRODUCTION:Intimate partner violence during pregnancy can contribute to maternal mortality and morbidity by limiting women's ability to receive maternal health services including antenatal care and skilled delivery care. In Ethiopia, evidence regarding
Abdulbasit Musa, Catherine Chojenta, Deborah Loxton   +2 more
doaj   +1 more source

Intimate Partner Violence and Sexual Violence in the Aleutian/Pribilof Island Region: Key Results from the 2014 and 2015 Alaska Victimization Surveys [PDF]

, 2018
This document is a two-page summary of the key results from the 2014–2015 Alaska Victimization Survey (AVS) for the Aleutian/Pribilof Island region, which was conducted from April to June 2014 and May to August 2015, with results released on March 13 ...
Rosay, André B.
core  

Men's and women's experiences of violence and traumatic events in rural Cote d'Ivoire before, during and after a period of armed conflict. [PDF]

, 2014
OBJECTIVE: We assessed men's and women's experiences of gender based violence and other traumatic events in Côte d'Ivoire, a West African conflict-affected setting, before, during and after a period of active armed conflict (2000-2007).
Bakayoko-Topolska, Monika, Hossain, Mazeda, Kiss, Ligia, Kone, Drissa, Lehmann, Heidi, Manan, David KA, Watts, Charlotte, Zimmerman, Cathy   +7 more
core   +2 more sources