Results 71 to 80 of about 59,439 (303)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Intimate Partner Violence in Chinese Societies [PDF]

open access: yes, 2011
The Chinese are the largest ethnic group in the world. In the United States, Chinese Americans are the largest Asian-American group, constituting about 22.6% of the Asian-American population (Uba, 1994). Although the number of studies on intimate partner
Chan, EKL
core  

Effect of physical intimate partner violence on body mass index in low-income adult women

open access: yesCadernos de Saúde Pública, 2015
This study aimed to assess whether physical intimate partner violence affects the nutritional status of adult women with different levels of body mass index (BMI).
Marcela de Freitas Ferreira   +5 more
doaj   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

open access: yesAdvanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong   +10 more
wiley   +1 more source

Cash transfers and intimate partner violence: What does the evidence say? [PDF]

open access: yes, 2019
Cash transfers are a popular tool to address poverty and food insecurity, but can they also reduce women’s risk of intimate partner violence?Non-PRIFPRI1; G Cross-cutting gender theme; CRP2; Cash Transfer and Intimate Partner Violence Research ...
Cash Transfer and Intimate Partner Violence Research Collaborative
core  

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Exploring the complex pathway of the primary health care response to intimate partner violence in New Zealand

open access: yesHealth Research Policy and Systems, 2018
Background Integrating sustainable responses to intimate partner violence in health care is a persistent and complex problem internationally. New Zealand holds a leading role, having established national health system infrastructure for responding to ...
Claire Gear   +2 more
doaj   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

Qualitative exploration of cognition in intimate partner violence offenders and intimate partner violence sex offenders research portfolio [PDF]

open access: yes, 2013
Aims: Recently, empirical literature exploring cognitive characteristics of intimate partner violence offenders has received considerable attention with both theory and practice historically focusing on victims of the abuse. Qualitative exploration has
Weldon, Sarah Elizabeth
core  

One stop crisis centres: A policy analysis of the Malaysian response to intimate partner violence. [PDF]

open access: yes, 2011
BACKGROUND: This article aims to investigate the processes, actors and other influencing factors behind the development and the national scale-up of the One Stop Crisis Centre (OSCC) policy and the subsequent health model for violence-response.
Manuela Colombini   +11 more
core   +1 more source

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