Results 121 to 130 of about 287,112 (303)

STRATEGIES AND TACTICS OF EFFECTIVE COMMUNCATION IN PROFESSIONAL SPHERE

Гуманитарные и юридические исследования, 2021
Tolerance development is of great current interest in the modern world. It is important not only for indulgence enhancement of different social groups to each other, but also for signiicant increase of eficiency of the modern economy.
E. A. Sidelnikova
doaj  

A Novel Constitutional TUBB Variant Associated With Familial Malformations of Cortical Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Most pathogenic tubulin variants arise de novo in sporadic patients, causing severe brain malformations and significant neurodevelopmental impairment. The resulting reproductive disadvantage typically prevents these mutations from being transmitted to offspring.
Elena Cellini, Davide Mei, Mara Cavallin, Simona Fiori, Luciana Tramacere, Maria Elena Melica, Giulia Antonelli, Simona Virdò, Elena Parrini, Renzo Guerrini   +9 more
wiley   +1 more source

Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC‐REFUSAL Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The benefit of left atrial appendage closure (LAAC) in patients refusing oral anticoagulation (OAC) despite medical recommendations is unknown. We aim to assess the efficacy and the safety of LAAC in patients refusing OAC.
Roberto Galea, Tommaso Bini, Kasper Korsholm, Alexander Sedaghat, Adel Aminian, Vivian Vij, Juan Perich Krsnik, Konstantina Chalkou, Georgios Siontis, Laurent Roten, Jens Erik Nielsen‐Kudsk, Lorenz Räber   +11 more
doaj   +1 more source

L‐Cysteine and N‐Acetylcysteine Supplementation Improves Clinical Outcome in a Patient With COXPD10

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT MTO1 is a nuclear gene that encodes a mitochondrial protein essential for modifying mitochondrial transfer RNAs (tRNAs) and stabilizing codon‐anticodon interactions to ensure accurate and efficient mitochondrial protein synthesis and oxidative phosphorylation.
Nishitha R. Pillai, Sara A. Elsbecker, Grace Bronken McCarthy, Kaitlin Weisshappel, Peter Karachunski, Fernando Scaglia   +5 more
wiley   +1 more source

Genetic Variation in ADHD‐Related Risk Genes in an Indigenous Population of the Amazon

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Attention‐Deficit/Hyperactivity Disorder (ADHD) is a highly heritable neurodevelopmental disorder; however, its genetic architecture remains poorly explored in Indigenous populations. This study aimed to analyze and characterize genetic variation in 11 genes (ADGRL3, CDH8, DCC, DUSP6, FOXP1, FOXP2, MEF2C, PCDH7, SEMA6D, SORCS3, and ST3GAL3 ...
Hirlesson Paixão de Matos, Natasha Monte, Kaio Evandro Cardoso Aguiar, Rita de Cássia Calderaro, Aline Pasquini Santos, Juliana Carla Gomes Rodrigues, André Maurício Ribeiro‐Dos‐Santos, Sandro José De Souza, Ândrea Ribeiro‐Dos‐Santos, João Farias Guerreiro, Sidney Emanuel Batista Dos Santos, Ney Pereira Carneiro Dos Santos   +11 more
wiley   +1 more source

CONCEPTUAL POWER AND ANTICORRUPTION MOVEMENT IN THE COUNTRY

Russian Journal of Economics and Law, 2013
Objective: To show the inconsistency of the functioning system of corruption counteraction in the country and necessity to elaborate the conception of anticorruption policy.
G. N. Gorshenkov
doaj  

Patient and Family Reported Clinical Picture of IRF2BPL‐Related Disorders

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT IRF2BPL‐related disorder is a neurodevelopmental disorder caused by heterozygous variants in the IRF2BPL (Interferon Regulatory Factor 2 Binding Protein‐Like) gene. The few reports available in the literature suggest that common symptoms include developmental delay, intellectual disability, and developmental regression.
Zoe Goldstone‐Joubert, Danielle M. Pascual, Laurie Anne Bailey, Loren D. M. Peña, Paul C. Marcogliese   +4 more
wiley   +1 more source

Religious intolerance

, 2023
Para establecer una base de entendimiento, la primera cuestión es determinar qué es la intolerancia religiosa; es decir, qué significa intolerancia, qué no puede entenderse como tolerancia y cuáles son sus límites.
Gutiérrez y Restrepo, Emmanuelle
core  

Metaanalysis of application effect of early hypocaloric enteral nutrition support in critically ill patients

Huli yanjiu, 2019
Objective:To systematically evaluate the application effect of early hypocaloric enteral nutrition support in critically ill patients.Methods:To retrieve randomized controlled trials related to early hypocaloric enteral nutrition support in critically ...
王芳, 姚志清, 陈璐, 傅巧美
doaj  

Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model

Annals of Neurology, EarlyView.
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau, Sebastien Arthaud, Leila Langbour, Silvia Melzi, Aurelie Richard‐Mornas, Hannah Doudoux, Benjamin Rolland, Laure Peter‐Derex, Christelle Peyron   +8 more
wiley   +1 more source