Pre‐treatment DPYD and UGT1A1 genotyping is increasingly used to prevent fluoropyrimidine‐ and irinotecan‐related toxicity, but variant‐specific real‐world effects remain unclear. In an unselected cohort of cancer patients with actionable genotypes, genotype‐driven dosing improved safety while preserving treatment exposure in high‐risk DPYD c.1905+1G>A
Martina Gambron +12 more
wiley +1 more source
Intolerance of uncertainty and attitudes toward cancer as predictors of spiritual well-being in patients with cancer. [PDF]
Vatansever E, Ciydem E.
europepmc +1 more source
ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Martin Griesshammer +8 more
wiley +1 more source
Acute Systemic Complications Following High-Dose Semaglutide Reinitiation in an Elderly Patient. [PDF]
Mehta J, Tai B, Frunzi J.
europepmc +1 more source
ABSTRACT The recommended adjuvant chemotherapy (adj‐ChT) regimen for resected biliary tract cancers (BTC) is capecitabine (Cape); yet, the recommendation is based on limited evidence. Although varied adj‐ChTs have been employed in practice, robust real‐world data is scarce. We conducted a national, multicenter, hospital‐based registry study to evaluate
Erman Akkus +60 more
wiley +1 more source
Non-Responder to Inclisiran and Evolocumab-A Female Patient with Heterozygous Familial Hypercholesterolemia and Statin Intolerance. [PDF]
Muszyński P +7 more
europepmc +1 more source
Novel Phenotype due to <i>KCNJ11</i> Pathogenic Variant Associated with Maturity-Onset Diabetes of the Young-KCNJ-11. [PDF]
Reunes M, Matthys I, Van Damme T.
europepmc +1 more source
Efficacy of personalized traditional Chinese medicine massage combined with tuina in the treatment of pediatric congenital heart disease and malnutrition intolerance. [PDF]
Wang Y, Yao J, Xiao Y, Ma Q, Tao S.
europepmc +1 more source
Graft Embolization versus Nephrectomy in Patients with Graft Intolerance and Infection: A Retrospective Cohort Study. [PDF]
Klaassen MF +7 more
europepmc +1 more source
Sex Differences in Statin Intolerance: Insights From the CLEAR Outcomes Trial. [PDF]
Naderi S +9 more
europepmc +1 more source

