Results 111 to 120 of about 272,039 (291)

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

open access: yesAdvanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao   +8 more
wiley   +1 more source

Intoxication and US Culture: An Interview with Craig Reinarman

open access: yesNANO, 2016
Intoxication and US Culture: An Interview with Craig Reinarman. Ingrid Walker interviews Craig Reinarman, Professor of Sociology and Legal Studies at the University of California, Santa Cruz.
Ingrid Walker, Craig Reinarman
doaj  

On the Fire Hazard of High-Rise Buildings and Skyscrapers

open access: yesТеория и практика судебной экспертизы
The article presents an analysis of fire hazard of high-rise buildings and skyscrapers. The author notes a range of factors significantly impacting on the course of emergency rescue operations, including the difficulty of evacuating people from the ...
I. S. Taubkin
doaj   +1 more source

Modulating Local Electronic Structure via Cluster Engineering on Cobalt Phosphide for Efficient Water/Seawater Splitting

open access: yesAdvanced Science, EarlyView.
The heterostructure benefits from the high dispersion of FeOx nanoclusters on the porous CoxP substrate, while the interfacial bonds Fe‐O‐Co enhance charge transport and redistribution, resulting in excellent oxygen evolution reaction performance and strong potential for practical applications.
Cheng Gong   +11 more
wiley   +1 more source

Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys

open access: yesAdvanced Science, EarlyView.
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin   +11 more
wiley   +1 more source

Cantharidin Poisoning due to Blister Beetle Ingestion in Children : Two case reports and a review of clinical presentations

open access: yesSultan Qaboos University Medical Journal, 2010
Cantharidin is an intoxicant found in beetles in the Meloidae (Coleoptera) family. Ingestion may result in haematemesis, impaired level of consciousness, electrolyte disturbance, haematurea and renal impairment.
Ali M. Al-Binali   +5 more
doaj  

Alcohol Use, Abuse, and Dependency in Shanghai [PDF]

open access: yes, 1992
The use of alcohol for social and ceremonial occasions was recorded in Chinese history as early as 1760 B.C. during the Yin Dynasty (Ci-Hai Encyclopedia, 1979:936).
Fernandez, Marilyn   +8 more
core   +1 more source

Metarhizium anisopliae Mitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

open access: yesAdvanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng   +7 more
wiley   +1 more source

Drug & alcohol use among LGBTS in the city of Leeds [PDF]

open access: yes, 2003
Project A Representatives from seven drug and alcohol organisations in Leeds were interviewed about the services they provide and how accessible they believe those services to be to be for lesbian, gay,bisexual and transgender (LGBT) communities in the ...
Noret, N, Rivers, I
core  

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy