Results 131 to 140 of about 105,922 (209)

Affected Persons in Laboratory Exposures to Human Pathogens and Toxins in Canada, 2016–2024: A Sector‐Specific Analysis

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Exposures to human pathogens and toxins in licensed facilities in Canada have been monitored by a federal surveillance system since 2015, yet the affected persons (APs) in these incidents remain uncharacterized. This study comprehensively describes APs, highlighting sector‐specific patterns and trends over time.
Emily F. Tran   +4 more
wiley   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

open access: yesAngewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang   +15 more
wiley   +2 more sources

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

open access: yesAdvanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora   +11 more
wiley   +1 more source

Constructing p‐d Orbital Hybridization via In Situ Generation of Bi19Br3S27/NiSx for Highly Selective Photothermal CO2 Reduction to C2H4

open access: yesAngewandte Chemie, EarlyView.
An in situ crystalline/amorphous Bi19Br3S27/NiSx interface unlocks orbital hybridization‐driven CO2 conversion. Newly formed p‐d coupling reshapes the reaction pathway, promotes C─C coupling, and steers photo‐thermal CO2 reduction toward highly selective C2H4 production.
Guangmei Gan   +6 more
wiley   +2 more sources

Redox‐Neutral Vicinal Dialkylation of Aryl Boronic Esters via the Palladium/Norbornene Cooperative Catalysis

open access: yesAngewandte Chemie, EarlyView.
A new mode of the palladium/norbornene (Pd/NBE) cooperative catalysis, that is, redox‐neutral difunctionalization of aryl boronic esters with two electrophiles, has been developed, which can be used to streamline the preparation of a functionalized benzoazepane.
Rong Ye   +4 more
wiley   +2 more sources

Heterobimetallic Janus Catalysts for the One‐Pot Synthesis of Polar‐Apolar Block Copolymers

open access: yesAngewandte Chemie, EarlyView.
Heterobimetallic Janus catalysts act as bifunctional initiators, combining two distinct polymerisation mechanisms in one pot to deliver well‐defined apolar‐polar block copolymers. Combining Earth abundant Ti and Al catalysts for respective α‐olefin and lactone polymerisation, the orthogonal activity is enabled by unprecedented initiation from a Ti ...
Raju Chambenahalli   +2 more
wiley   +2 more sources

The Promise and Challenges of Ammonia Electrosynthesis From Dinitrogen and Water Using an Electrochemical Palladium Membrane

open access: yesAngewandte Chemie, EarlyView.
Electrosynthesis of ammonia from nitrogen gas and water at ambient temperature is demonstrated using a device equipped with an electrochemical palladium membrane, which provides exclusive selectivity for the transfer of protons between the aqueous water oxidation and non‐aqueous nitrogen reduction compartments.
Ngoc‐Trung Nguyen   +11 more
wiley   +2 more sources

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