Results 171 to 180 of about 1,407,869 (246)

Free‐Breathing Fat Quantification Using a Phase Error‐Corrected Cartesian Acquisition With Spiral Profile Ordering

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1709-1725, October 2026.
ABSTRACT Purpose To develop a phase‐corrected time‐interleaved multi‐echo gradient echo Cartesian acquisition with spiral profile ordering (TIMGRECASPR) for abdominal large‐FOV proton density fat fraction (PDFF) mapping at 3 T, demonstrating its sampling flexibility and inherent self‐gating capabilities at high isotropic resolutions.
Philipp Braun   +7 more
wiley   +1 more source

Optimal Control‐Based RF Pulses Versus Classical Motion‐Encoding Strategies for In Vivo Hepatic MR Elastography Across Multiple Excitation Frequencies in Mice: Reproducibility Assessment

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
Optimal control (OC)–based motion encoding doubles SNR in vivo in murine hepatic MRE by eliminating motion‐encoding gradients and enabling shorter echo times. Quantitative liver stiffness measurements remain consistent with conventional MEG‐MRE across multiple excitation frequencies, supporting longitudinal studies and clinical translation ...
Tiffany Bakir‐Ageron   +5 more
wiley   +1 more source

Uterus‐preserving surgery for placenta accreta spectrum: An expert, illustrated review of techniques and its outcomes

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1932-1949, October 2026.
Uterus‐preserving strategies for PAS include myometrial resection and leaving placenta in situ, differing in surgical principles, complications, and follow‐up. Myometrial resection offers definitive treatment with lower rates of delayed morbidity, while leaving the placenta in situ minimizes surgical risk but is associated with prolonged follow‐up ...
Pedro Viana Pinto   +6 more
wiley   +1 more source

Transumbilical laparoendoscopic single‐site surgery versus conventional multi‐port laparoscopy for myomectomy: A large single‐center retrospective study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 2068-2080, October 2026.
This retrospective observational study compared clinical outcomes from patients who underwent transumbilical laparoendoscopic single‐site surgery (single‐site laparoscopy) or conventional multi‐port laparoscopy for myomectomy. Single‐site laparoscopy and multi‐port laparoscopy showed similar performance in terms of surgical safety.
Xu Yang   +11 more
wiley   +1 more source

Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord‐Injured Humans: A Narrative Review

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three
Rasmus Kopp Hansen   +5 more
wiley   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam   +4 more
wiley   +1 more source

Assessing the Diagnostic Performance of Triglyceride–Glucose–Based Indices for Early Detection of Metabolic Syndrome in Paediatric Down Syndrome

open access: yesJournal of Intellectual Disability Research, Volume 70, Issue 10, Page 1022-1032, October 2026.
ABSTRACT Background Down syndrome (DS) youth have an increased risk of metabolic syndrome (MetS). This study assessed the diagnostic performance of the triglyceride–glucose index (TyG) and its derivatives—TyG‐BMI, TyG‐waist circumference (WC) and TyG‐waist‐to‐height ratio (WHtR) in detecting MetS compared with traditional markers.
Valeria Calcaterra   +5 more
wiley   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

open access: yesObesity Reviews, Volume 27, Issue 10, October 2026.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, Volume 20, Issue 9, Page 2203-2219, September 2026.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu   +11 more
wiley   +1 more source

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