Results 191 to 200 of about 1,407,869 (246)
Early pregnancy vitamin D deficiency in women with overweight or obesity is associated with greater increases in LDL cholesterol and ketone bodies during gestation, as well as higher cord blood ketone levels in offspring. These findings suggest a role of maternal vitamin D status in shaping metabolic adaptations in pregnancy and fetal exposure ...
Jürgen Harreiter +24 more
wiley +1 more source
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed +8 more
wiley +1 more source
Schisandrin B ameliorates stress‐provoked anxiety‐like behaviors in rats via restoring intestinal barrier tight‐junction integrity, balancing hippocampal glutamate‐GABA neurotransmission, and promoting hippocampal synaptic plasticity. ABSTRACT This study focused on examining the anxiolytic effects of Schisandrin B (SchB) in rats exhibiting anxiety‐like
Jia‐Yu Tian +7 more
wiley +1 more source
Gut Microbiota Dysbiosis Mediates 125I‐Induced Radiation Colitis via Host Transcriptional Regulation
ABSTRACT Background Iodine‐125 (125I) seed therapy is recognized for treating abdominal solid tumors with minimal adjacent tissue damage but may induce radiation colitis when its implantation near colonic tissues, leading to a poor prognosis. Nevertheless, the underlying pathogenesis is not well understood.
Pingping Liu +8 more
wiley +1 more source
Natural Product‐Derived Vesicles in Nanotherapeutics
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley +1 more source
This narrative review synthesises current literature regarding paediatric blunt abdominal trauma imaging. It discusses the diagnostic performance of Focused Assessment with Sonography for Trauma, unenhanced and contrast‐enhanced ultrasound, as well as the impact of clinical decision rules for CT on clinical outcomes and radiation dose savings ...
Gemma Dongwon Lee +5 more
wiley +1 more source
Intra-abdominal fat evaluation system by utilizing ultrasound technology
Koizumi, Norihiro +9 more
openaire +1 more source
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease.
Jake P. Mann +30 more
wiley +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Unveiling Functional Architecture of Human Thalamus: AStereoelectroencephalography Study
The human thalamo‐cortical loop underpins complex behavior and is implicated in a wide range of neurological and psychiatric disorders, yet its functional organization remains incompletely understood. Using direct electrical stimulation combined with the human functional connectome, we mapped the functional architecture of the human thalamus and ...
Liankun Ren +24 more
wiley +1 more source

