Results 51 to 60 of about 574,306 (307)

Intra-articular injection of human umbilical cord-derived mesenchymal stem cells in sheep models of meniscectomy-induced osteoarthritis: An experimental study

Orthopaedic Journal of Sports Medicine, 2023
Introduction: Autologous mesenchymal stem cells (MSC) implantation suspended in hyaluronic acid (HA) has been proven to delay worsening of articular cartilage degeneration in the knee joint.
Andri Maruli Tua Lubis, Adrian Situmeang, Anissa Feby Canintika, Mawar Subangkit, Handina Rakhmawati, Stefan Nugroho, Matheus Alvin Prawira, Harry Murti, Arief Boediono   +8 more
doaj   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

reDuction oF acute anterior sHoulDer Dislocations: comParing intraarticular lignocaine witH intravenous anestHesia

Journal of Nepal Medical Association, 2006
Anterior shoulder dislocation is the most common dislocation in the body. Various methods of anesthesia are available for reduction. The objective of this study was to compare the application of intra-articular anesthesia with intravenous anesthesia ...
Rabindra L Pradhan, S Lakhey, B K Pandey, K P Rijal   +3 more
doaj   +1 more source

Anterior Electronic Hip Pain Drawings Are Helpful for Diagnosis of Intra-articular Sources of Pain: Lateral or Posterior Drawings Are Unreliable

Arthroscopy, Sports Medicine, and Rehabilitation, 2023
Purpose: The purpose of this study was to determine the accuracy of electronic hip pain drawing to diagnose intra-articular source of pain in nonarthritic hips, defined by response to an intra-articular injection.
Richard Feng, M.P.H., Munif Hatem, M.D., M.S., Hal David Martin, D.O.   +2 more
doaj   +1 more source

Efeito hiponociceptivo da histamina intra-articular [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2009.Histamina é encontrada no líquido sinovial de pacientes indivíduos saudáveis e em diversos ...
Silva, Eduardo Souza
core  

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

Advanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin, Zijian Yan, Jiayi Chen, Xiaochao Wang, Ruibin Lin, Yunqi Fu, Zhaoying Lv, Bohui Wu, Xuewei Cao, Renjian Xie, Ming Dong, Chenxiao Zheng, Li Ren   +12 more
wiley   +1 more source

Pharmacokinetics of amikacin after intravenous, intra‐articular, and combined intravenous and intra‐articular administration in healthy neonatal foals

Journal of Veterinary Internal Medicine
Background Pharmacokinetics of amikacin administered IV to neonatal foals are described, but little data are available regarding the plasma concentrations contributed by concurrent intra‐articular (IA) administration.
Jillian L. Paegelow, Mike J. Schoonover, Jenna M. Young, Lara K. Maxwell, Jared D. Taylor, Lyndi L. Gilliam, Todd C. Holbrook   +6 more
doaj   +1 more source

Efficacy of Combined Intra-articular Steroids and Calcitonin Nasal Spray versus Intra-articular Steroids Alone in the Management of Early Frozen Shoulder: A Prospective Study

Introduction: Frozen shoulder is one of the commonest debilitating conditions with characteristic features of by pain and globally restricted range of motion of the shoulder.
Gaurav Kumar Sharma, Ramesh Negi, Amit Kumar Salaria, Sukhmin Singh   +3 more
core   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

A Comparison of the Efficacy of Intra-Articular Injection of Morphine with Marcaine in Patients to Relief the Pain Associated with

Journal of Mazandaran University of Medical Sciences, 2007
. *AbstractBackground and purpose: Knee arthroscopy is an approved technique for the diagnosis and treatment of intra-articular lesions. Moderate to severe pain is experienced after surgery; thus, relieving pain post arthroscopy, will help patients in ...
S.E. Shafiei,, M.H. Karimi nasab, M.D, M. Shayesteh azar, M.D, M. Shayesteh azar, M.D, M. Sajjadi, M.D   +4 more
doaj