Results 61 to 70 of about 900,387 (301)

Pharmacokinetics of amikacin after intravenous, intra‐articular, and combined intravenous and intra‐articular administration in healthy neonatal foals

Journal of Veterinary Internal Medicine
Background Pharmacokinetics of amikacin administered IV to neonatal foals are described, but little data are available regarding the plasma concentrations contributed by concurrent intra‐articular (IA) administration.
Jillian L. Paegelow, Mike J. Schoonover, Jenna M. Young, Lara K. Maxwell, Jared D. Taylor, Lyndi L. Gilliam, Todd C. Holbrook   +6 more
doaj   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Biomechanical evaluation of intra-articular and extra-articular procedures in anterior cruciate ligament reconstruction: A finite element analysis [PDF]

Background. Intra-articular techniques (single and double bundles) are the most widely used procedures for the anterior cruciate lig- ament reconstruction.
Siegrist, O., Saunier, P., Pioletti, Dominique P., Ramaniraka, N.A.   +3 more
core   +2 more sources

Controversy of high tibial osteotomy

Journal of Limb Lengthening & Reconstruction, 2015
The medial compartment osteoarthritis (OA) of knee joint has various surgical options such as high tibial osteotomy (HTO), hemiarthroplasty, and total knee arthroplasty. In the early stages of medial OA, there are no intra-articular deformities. Thus HTO,
Tsukasa Teramoto
doaj   +1 more source

Imaging characteristics of tenosynovial giant cell tumors on 18F-fluorodeoxyglucose positron emission tomography/computed tomography: a retrospective observational study

BMC Musculoskeletal Disorders, 2023
Background 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) is useful for assessing location, metastasis, staging, and recurrence of malignant tumors.
Kohei Mizuta, Hiromichi Oshiro, Yuichi Tsuha, Yasunori Tome, Kotaro Nishida   +4 more
doaj   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Measurements of the intra-articular graft length.

, 2016
(A) The measurement of the intra-articular length of anterolateral bundle graft. (B) The measurement of the intra-articular length of posteromedial bundle graft.
Caiqi Xu (2793544), Yang Zhang (30734), Jinzhong Zhao (2175712), Shikui Dong (385161), Song Zhao (75272), Peng Shen (688111), Xiaoxi Li (255922)   +6 more
core   +1 more source

Efficacy of Intra-articular Versus Extra-articular Bupivacaine Injection in Arthroscopic Partial Meniscectomy: A Prospective, Randomized, Double-Blind Clinical Trial

Orthopaedic Journal of Sports Medicine, 2023
Background: Immediate postoperative pain relief following arthroscopic partial meniscectomy remains a critical contributor to improved patient experience, early recovery of range of motion, and enhanced rehabilitation.
Dror Lindner MD, Ron Gilat MD, Yossi Smorgick MD, Erez Avisar MD, Gabriel Agar MD, Yiftah Beer MD   +5 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source