Results 141 to 150 of about 1,686,049 (292)

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Risk of septic arthritis following corticosteroid and platelet‐rich plasma injections: A multicenter retrospective review

PM&R, EarlyView.
Abstract Background Platelet‐rich plasma injections (PRPI) are a relatively new and evolving treatment option for a variety of musculoskeletal injuries. It has been theorized that there is an increased risk of septic arthritis (SA) with PRPI, though there have been no dedicated studies to assess the incidence of SA and only three cases have been ...
Kory Ford, James Frazier, Anthony Beutler, Catherine Fairgrieve Appel, Daniel M. Cushman   +4 more
wiley   +1 more source

Can intra-articular therapies prior to total knee arthroplasty increase the risk of periprosthetic infection?

, 2015
Intra-articular therapies, such as steroid injection, viscosupplement injection and acupuncture, are common non-surgical options for patients with osteoarthritis of the knee.
Azhanie Sardangi
core  

Emerging Approaches for Phytoconstituent Delivery in the Management of Rheumatoid Arthritis: Bridging Nature and Nanotechnology

Phytotherapy Research, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is an autoimmune condition marked by joint inflammation, cartilage destruction, and bone damage. Conventional treatments, including NSAIDs and DMARDs, have shown effectiveness in slowing down disease progression, but prolonged exposure to such medications results in adverse effects and lack of tolerance among patients.
Yogesh Khairnar, Sakshi Priya, Madhavi Rajpara, Venkatesh K. P. Rao, Geeta Bhatt, Gautam Singhvi   +5 more
wiley   +1 more source

Biomaterial Platforms for Spatiotemporal Control of mRNA Delivery in Tissue Engineering and Regenerative Medicine: Design Rules, Therapeutic Applications, and Translational Roadmap

Small, EarlyView.
Biomaterial platforms can control where and when mRNA‐encoded proteins are expressed to support tissue repair. This Review proposes a cargo–target–timing framework linking therapeutic function, target tissues and cells, and expression profiles with carrier and scaffold design.
Huachun Pan, Shumin Yang, Katarina Holubova, Huifang Yin, Hongbo Chen, Xintian Zheng, Xiangan Han, Jinqiu Zhang, Xueping Li, Hui Zhang, Xiaojun Cai, Václav Slovák, Lihong Zhang, Quan Mo, Quazi T. H. Shubhra   +14 more
wiley   +1 more source

Perioperative analgesia and postoperative motor function after saphenous and sciatic nerve blocks in goats undergoing bilateral stifle surgery: A pilot study

Veterinary Record, EarlyView.
Abstract Background The combination of femoral and sciatic nerve blocks offers adequate perioperative analgesia for goats undergoing stifle surgery. However, postoperatively, residual motor dysfunction may lead to distress and discomfort. This study evaluated whether combined saphenous and sciatic nerve blocks provide adequate perioperative analgesia ...
Xavier Torruella, Claire Loughran, Flavia Restitutti, Joei Potter, Margot C. Labberté, Pieter A. J. Brama, Vilhelmiina Huuskonen   +6 more
wiley   +1 more source

PROSPECT guideline for total hip arthroplasty: updated systematic review and procedure‐specific postoperative pain management recommendations

Anaesthesia, EarlyView.
Summary Introduction The Procedure Specific Postoperative Pain Management (PROSPECT) collaboration develops evidence‐based recommendations integrating analgesic efficacy, safety and functional recovery. Since publication of the 2021 PROSPECT guidelines for total hip arthroplasty, new evidence, particularly on motor‐sparing regional techniques, has ...
Michele Carella, Dario Bugada, Marc Van de Velde, Helene Beloeil, Eric Albrecht, Patricia Lavandhomme, Johan Raeder, Girish P. Joshi, on behalf of the PROSPECT Working Group of the European Society of Regional Anesthesia and Pain Therapy   +8 more
wiley   +1 more source

Canadian evidence‐based guidelines on spinal procedures for chronic pain

Anaesthesia, EarlyView.
Summary Introduction Interventional procedures are commonly used to diagnose and treat chronic pain of spinal origin but guidance on: their indications; frequency; technical conduct; requirements for image guidance; outcome measurement; and management of complications is lacking.
Anuj Bhatia, Philip Peng, Harsha Shanthanna, Yasmine Hoydonckx, James S. Khan, Elad Dana, Abeer Alomari, Tarvit Worravitudomsuk, Howard Meng, Martina Rekatsina, Ian Gilron, Andrea D. Furlan, Norman Buckley, Ian Beauprie, Roderick Finlayson, Paul Etheridge, Eldon Loh, Christopher Mares, Mohan Radhakrishna, Sebastian Mafeld, John X. Pereira, Hance Clarke, Shawn Marshall, Magali Robert, Pam Squire, Robert Tanguay, Danielle Alvares   +26 more
wiley   +1 more source

Is intra-articular injection of high-concentration ozone (O2-O3) more effective in treating knee osteoarthritis?: A multicenter cohort study. [PDF]

Medicine (Baltimore)
Isik R, Yildiz B, Unver S, Sencan S, Kokar S, Gunduz OH, Gunduz OH, Uzun E, Nas K.   +8 more
europepmc   +1 more source

SiGnature: Explicit Motion Diffusion for Stylized Semantic Gesture Generation

Computer Graphics Forum, EarlyView.
Abstract While recent advances in co‐speech gesture generation have achieved impressive rhythmic synchronization, synthesizing gestures that are both semantically meaningful and faithful to a speaker's unique non‐verbal style remains an open challenge.
Adi Rosenthal, Tomer Koren, Nadav Shaked, Doron Friedman, Ariel Shamir   +4 more
wiley   +1 more source