Results 151 to 160 of about 1,686,049 (292)

Drug-loaded nanoparticles for intra-articular injection. [PDF]

open access: yesPLoS One
Pan P   +10 more
europepmc   +1 more source

Intra-Articular Injection of PLGA/Polydopamine Core–Shell Nanoparticle Attenuates Osteoarthritis Progression

open access: yes
Osteoarthritis (OA) is a common joint disease characterized by progressive cartilage degeneration. Unfortunately, currently available clinical drugs are mainly analgesics and cannot alleviate the development of OA.
Lujie Zong (18424331)   +8 more
core   +1 more source

Purpurin Alleviates Meniscal Senescence and Osteoarthritis by Blocking the Non‐Metabolic Function of Hexokinase 2

open access: yesCell Proliferation, EarlyView.
HK2 is upregulated in osteoarthritis and accelerates disease progression via a glycolysis‐independent non‐metabolic mechanism. It recruits PRKN to degrade MYH10, reducing COL1A1 mRNA stability and inducing senescence. Purpurin disrupts this pathogenic pathway with therapeutic potential.
Zhencan Lin   +9 more
wiley   +1 more source

Anaesthetic management of a horse with acute kidney injury

open access: yesEquine Veterinary Education, EarlyView.
Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley   +1 more source

Computed tomographic arthrography of the coxofemoral joint in horses

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Investigation of pathology relating to the coxofemoral joint (CFJ) in horses includes intra‐articular analgesia and diagnostic imaging using ultrasonography, radiography, scintigraphy and computed tomography (CT). While CT arthrography has been described for diagnosing intra‐articular ligament and cartilage injuries in different ...
S. J. Attin   +2 more
wiley   +1 more source

Severe neck stiffness in a 20‐year‐old gelding with cytological findings suggestive of cervical vertebral neoplasm

open access: yesEquine Veterinary Education, EarlyView.
Summary A 20‐year‐old warmblood gelding was referred for the evaluation of severe cervical stiffness and pain. Radiographic examination revealed marked arthropathy of the C3–C4 articular processes, with severe remodelling and narrowing of the C3–C4 intervertebral space.
F. Bonaspetti   +4 more
wiley   +1 more source

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