Results 131 to 140 of about 6,871 (232)

From patient notes to prognostication: The revolutionary potential of event‐based foundation models in orthopaedics

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The integration of artificial intelligence (AI)‐equipped tools into electronic health record (EHR) platforms may drive the evolution of orthopaedic diagnosis and decision‐making, leveraging big data to generate precise and context‐aware insights.
Alexander M. Bouterse, James A. Pruneski, Felix C. Oettl, Bálint Zsidai, Umile Giuseppe Longo, Thomas Tischer, Michael T. Hirschmann, Kristian Samuelsson   +7 more
wiley   +1 more source

Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran, Korry T. Wirth, Matthew M. Byrne, Benjamin Gertsen, Eric Y. Wang, Darrian S. Hawryluk, Martin S. Pavelka, Nicole A. Wilson   +7 more
wiley   +1 more source

The Effect of Intra-Articular Injections of Hyaluronic Acid for the Treatment of Trapezio-Metacarpal Joint Osteoarthritis

Background: Osteoarthritis of the basal thumb joint is a debilitating disease with a high prevalence. Among pharmacological treatments, intra-articular injections of hyaluronic acid have been clinically applied.
Federica Alviti, Nikolaos Finamore, Francesco Agostini, Marco Paoloni, Massimiliano Mangone, Elena Bressanin, Valter Santilli, Alessandro de Sire, Andrea Bernetti   +8 more
core   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Physician Responses to a Subsidy Removal: The Case of Joint Injections Under Australia's Medicare Program

Economic Record, EarlyView.
This study examines the effects of a public subsidy withdrawal on provider behaviour, focusing on General Practitioners (GPs) in Australia. Specifically, it explores changes in GP billing practices following the removal of an item on the Medicare Benefits Schedule that subsidises joint injections (intra‐articular steroids).
Olukorede Abiona, Maryam Naghsh‐Nejad, Kees Van Gool, Phil Haywood, Jane Hall   +4 more
wiley   +1 more source

Effect of intra-articular Botulinum toxin injections on temporo-mandibular joint pain

, 2018
International audienceTemporo-mandibular joint dysfunction can be painful and disabling. In some cases, it is refractory to classical treatment. Intra-articular Botulinum toxin injections have been shown to have an anti-inflammatory and analgesic effect.
A. Huart, D. Batifol, Huart, A., Nagot, N., N. Nagot, P.J. Finiels, P. Jammet, Jammet, P., Finiels, P.J., Batifol, D.   +9 more
core   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Musculoskeletal health among adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the burden of, and investigate prognostic factors for, osteoarthritis, osteopenia and/or osteoporosis, spondylosis, and fracture, and to investigate the effectiveness of protocols for monitoring musculoskeletal disorders and interventions for managing osteoarthritis in adults with cerebral palsy (CP).
Jennifer M. Ryan, Jessica Burke, Rachel Byrne, Emily Capellari, Christina M Marciniak, Maram Sofiany, Reuel Jalal, Mark Peterson, The Adult CP Clinical Practice Guideline Working Group, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms   +11 more
wiley   +1 more source

Updates on intra‐articular corticosteroid administration in horses

Equine Veterinary Education, EarlyView.
Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner, L. Bass, C. Kawcak, L. V. Schnabel, K. L. Hallowell, L. M. Pezzanite   +5 more
wiley   +1 more source