Results 221 to 230 of about 872,133 (249)

A simple maximum intensity projection method for measuring proximal femoral anteversion: An observer reliability study

open access: yesJournal of Experimental Orthopaedics, Volume 13, Issue 4, October 2026.
Abstract Purpose Quantifying femoral neck anteversion (FNA) is essential in lower limb torsional deformities. Because of proximal femur anatomy and computed tomography (CT) acquisition, the femoral head and neck are often visualized on different slices, making identification of the femoral‐head–neck axis (FHNA) challenging.
Marco Bechis   +7 more
wiley   +1 more source

Injectable autologous chondrocyte transplantation yields sustained clinical mid‐term improvement in acetabular cartilage defects in femoroacetabular impingement: A comparative analysis from the German Cartilage Registry (KnorpelRegister DGOU)

open access: yesJournal of Experimental Orthopaedics, Volume 13, Issue 4, October 2026.
Abstract Purpose To evaluate mid‐term outcomes of injectable matrix‐associated autologous chondrocyte transplantation (MACT) for acetabular cartilage defects in femoroacetabular impingement (FAI), comparing two different ACT products (NOVOCART® Inject vs. Chondrosphere®) using data from the German Cartilage Registry. Methods This retrospective analysis
Moritz Riedl   +8 more
wiley   +1 more source

M2 Macrophage‐Derived Small Extracellular Vesicle miR‐106a‐Loaded QCG Hydrogel Targets the RNF128‐LXR Pathway to Reprogram Chondrocyte Cholesterol Metabolism for Osteoarthritis Therapy

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Schematic illustration of the molecular mechanisms by which the inflammation‐responsive, injectable hydrogel QCG@sEV‐miR‐106a exerts therapeutic effects in OA. ABSTRACT This study addresses osteoarthritis (OA), in which dysregulated chondrocyte cholesterol homeostasis and cellular senescence contribute to cartilage degeneration, by developing an ...
Baozhe Liu   +5 more
wiley   +1 more source

Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis

open access: yesLasers in Surgery and Medicine, Volume 58, Issue 8, Page 644-655, October 2026.
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran   +7 more
wiley   +1 more source

Evaluation of the Efficacy of Photobiomodulation Therapy, Therapeutic Ultrasound, and Boric Acid in the Prevention of Intra‐Abdominal Adhesions in an Experimental Rat Model: A Macroscopic, Histopathological, and Gene Expression Analysis

open access: yesLasers in Surgery and Medicine, Volume 58, Issue 8, Page 656-671, October 2026.
ABSTRACT Objectives This study aimed to evaluate the efficacy of photobiomodulation therapy (PBMT), therapeutic ultrasound (TUS), boric acid (BA), and their combinations in preventing experimentally induced intra‐abdominal adhesions in rats. Materials and Methods Ninety‐six male Wistar rats (14 weeks old) were randomly assigned to eight groups (Control,
Sıtkıcan Okur   +10 more
wiley   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo   +4 more
wiley   +1 more source

Effects of Using High‐Frequency TENS During an Exercise Therapy Program in Knee Osteoarthritis: A Randomized Sham‐Controlled Trial

open access: yesPhysiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Background and Purpose Therapeutic exercise is central to knee osteoarthritis (KOA) management, but movement‐evoked pain may limit adherence and outcomes. High‐frequency transcutaneous electrical nerve stimulation may reduce pain during movement and enhance exercise‐related outcomes.
Patrícia Gabrielle dos Santos   +7 more
wiley   +1 more source

Evasins: Biology and Therapeutic Potential of Broad‐Spectrum Chemokine Inhibitors

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Ticks are haematophagous parasites that rely on uninterrupted bloodmeals for survival and need an effective strategy to suppress the host inflammatory response. Leukocyte recruitment is a chemokine‐mediated hallmark of inflammation, which ticks counteract via anti‐chemokine proteins in their saliva named evasins.
Emilia L. Bialek   +3 more
wiley   +1 more source

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