Results 31 to 40 of about 5,621,565 (249)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

High Efficiency Intra CU Partition and Mode Decision Method for VVC

, 2022
Versatile video coding (VVC/H.266) is the newest video compression standard, which is developed by the Joint Video Experts Team. Compared with previous encoding schemes, VVC achieves higher compression efficiency by introducing a new partition structure ...
Shih-Hsiang Lin, Yu-Ting Chu, Chi-Ting Ni, Pei-Yin Chen   +3 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Highly Parallel Rate-Distortion Optimized Intra-Mode Decision on Multicore Graphics Processors [PDF]

, 2009
Rate-distortion (RD)-based mode selections are important techniques in video coding. In these methods, an encoder may compute the RD costs for all the possible coding modes, and select the one which achieves the best trade-off between encoding rate and ...
Wong, Peter H.W., Au, Oscar C., null Man-Cheung Kung, Liu, Chun Hung, null Ngai-Man Cheung, Cheung, Ngai Man, Kung, Man Cheung, O.C. Au, null Chun Hung Liu, P.H.W. Wong   +9 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Edge information based effective intra mode decision algorithm

, 2012
In this paper, we present very simple, yet efficient, algorithms for intra mode decision algorithms in AVS video coding based on edges detection and neural network.
Yuan, Yule, Sun, Xiaohang, Xiaohang Sun, Yule Yuan   +3 more
core   +1 more source

Bitplane intra coding with decoder-side mode decision in distributed video coding [PDF]

, 2010
While distributed video coding (DVC) has emerged as a new video coding paradigm, the compression performance of current systems is still low compared to conventional solutions such as H.264/AVC.
Skorupa, Jozef, Peter Lambert, Adrian Munteanu, Van de Walle, Rik, Nikos Deligiannis, Munteanu, Adrian, Mys, Stefaan, Jozef Skorupa, Stefaan Mys, Lambert, Peter, Jurgen Slowack, Deligiannis, Nikos, Slowack, Jürgen, Rik Van de Walle   +13 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Fast Intra Mode Decision Algorithm for H264/AVC HD Baseline Profile Encoder

, 2012
International audienceThe high performance of H.264/AVC video encoder is accompanied with a wide computation complexity especially for high definition (HD) video sequences. One of the major H.264/AVC features to be optimized is the mode decision for both
Samet, Amine, Bahri, Nejmeddine, Werda, Imen, Ali Ben Ayed, Mohamed, Masmoudi, Nouri   +4 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source