Results 111 to 120 of about 3,321,426 (398)
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Aim. Comparative phenotypical and genetical evaluation ofpathogenic potential of Staphylococcus aureus strains, isolated from resident bacterial carriers, residing on the territories with anthropogenic pollution of air environment of varying intensity ...
T. M Utkina +4 more
doaj
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
ROLE OF BIOLOGICAL PROPERTIES OF CORYNEBACTERIA IN ASSOCIATIVE SYMBIOSIS
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Microorganisms of the Corynebacterium genus are examined in the review as a component of a single microecological system of humans in the context of their interaction with the macroorganism, dominant and associative microorganisms under the conditions of
I. V Gladysheva, S. V Cherkasov
doaj
Two intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2
, 2019 Placozoa is an enigmatic phylum of simple, microscopic, marine metazoans(1,2). Although intracellular bacteria have been found in all members of this phylum, almost nothing is known about their identity, location and interactions with their host(3-6). We
Dubilier, N. +7 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Intracellular cholesterol transport
Journal of Lipid Research, 1997 Recent data on the roles of vesicle- and 'raft'-mediated pathways in intracellular free cholesterol (FC) transport are reviewed. Cholesterol internalized from plasma lipoproteins is transferred via endocytic vesicles to the trans-Golgi network (TGN), consistent with prior data indicating a key role for this organelle in protein and lipid sorting and ...
C J Fielding, P E Fielding
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Antibodies, 2013 Many human diseases are caused by mutant or abnormal protein functions that are largely confined to the inside of cells, rather than being displayed on the abnormal cell surface. Furthermore, many of the functional consequences of aberrant proteins, such
Terence H. Rabbitts +3 more
doaj +1 more source
The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells. [PDF]
, 1996 Thymocytes must bind major histocompatibility complex (MHC) proteins on thymic epithelial cells in order to mature into either CD8+ cytotoxic T cells or CD4+ helper T cells.
Corbella, P +5 more
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