Results 161 to 170 of about 281,844 (353)

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani

, 2019
Visceral leishmaniasis (VL) is associated with treatment complications due to the continued growth of resistant parasites toward currently available pathogen-directed therapeutics.
Ainslie, Kristy M., Zahid, M. Shamim Hasan, Bachelder, Eric M., Tokarski, Robert J., Satoskar, Abhay R., Johnson, Monica M., Fuchs, James R.   +6 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Correction: The intracellular pathogen Francisella escapes from adaptive immunity by metabolic adaptation. [PDF]

Life Sci Alliance, 2022
Shibata K, Shimizu T, Nakahara M, Ito E, Legoux F, Fujii S, Yamada Y, Furutani-Seiki M, Lantz O, Yamasaki S, Watarai M, Shirai M.   +11 more
europepmc   +1 more source

Embedding Biomimetic Magnetic Nanoparticles Coupled with Peptide AS-48 into PLGA to Treat Intracellular Pathogens [PDF]

, 2022
Salvatore Calogero Gaglio, Ylenia Jabalera, Manuel Montalbán‐López, Ana Cristina Millán-Placer, Marina Lázaro, Mercedes Maqueda, Marı́a P. Carrasco, Alejandro Laso, José A. Aı́nsa, Guillermo R. Iglesias, Massimiliano Perduca, Concepción Jiménez-López   +11 more
openalex   +1 more source

Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing

Advanced Healthcare Materials, EarlyView.
We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu, Jiangtao Zhou, Yang Shen, Qiyao Sun, Tong Li, Xiaoyang Zou, Bin Liu, Hongshan Liang, Raffaele Mezzenga   +8 more
wiley   +1 more source

Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate. [PDF]

JCI Insight, 2023
Baars I, Jaedtka M, Dewitz LA, Fu Y, Franz T, Mohr J, Gintschel P, Berlin H, Degen A, Freier S, Rygol S, Schraven B, Kahlfuß S, van Zandbergen G, Müller AJ.   +14 more
europepmc   +1 more source

Nanomedicine as an emerging approach against intracellular pathogens

, 2011
Andrea L Armstead1–3, Bingyun Li1–31Biomaterials, Bioengineering and Nanotechnology Laboratory, Department of Orthopedics, School of Medicine, West Virginia University, Morgantown, WV; 2Pharmaceutical and Pharmacological Sciences ...
Armstead AL, Li B
core  

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Multiple refractory intracellular pathogen infections in a human immunodeficiency virus-negative patient with anti-interferon-γ autoantibodies: a case report. [PDF]

BMC Infect Dis, 2023
Wang H, Lei R, Ji Y, Xu W, Zhang K, Guo X.   +5 more
europepmc   +1 more source

Molecular methods to investigate adhesion, transmigration, invasion and intracellular survival of the foodborne pathogen Campylobacter jejuni

, 2013
Campylobacter jejuni is a spiral-shaped Gram-negative pathogen and major agent of gastrointestinal foodborne illness in humans worldwide. This pathogen encodes numerous described pathogenicity-associated factors involved in important processes including ...
Backert, Steffen, Hofreuter, Dirk
core   +1 more source