Results 141 to 150 of about 1,012,172 (301)

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Differential Transcriptomic Profile of Piscirickettsia salmonis LF-89 and EM-90 During an In Vivo Spatial Separation Co-Culture in Atlantic Salmon

Microorganisms
Salmonid rickettsial septicemia (SRS) is a critical sanitary problem in the Chilean aquaculture industry since it induces the highest mortality rate in salmonids among all infectious diseases.
Gabriela Carril, Hanne C. Winther-Larsen, Marie Løvoll, Henning Sørum   +3 more
doaj   +1 more source

Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate. [PDF]

JCI Insight, 2023
Baars I, Jaedtka M, Dewitz LA, Fu Y, Franz T, Mohr J, Gintschel P, Berlin H, Degen A, Freier S, Rygol S, Schraven B, Kahlfuß S, van Zandbergen G, Müller AJ.   +14 more
europepmc   +1 more source

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

The intracellular pathogen Francisella tularensis escapes from adaptive immunity by metabolic adaptation. [PDF]

Life Sci Alliance, 2022
Shibata K, Shimizu T, Nakahara M, Ito E, Legoux F, Fujii S, Yamada Y, Furutani-Seiki M, Lantz O, Yamasaki S, Watarai M, Shirai M.   +11 more
europepmc   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Multiple refractory intracellular pathogen infections in a human immunodeficiency virus-negative patient with anti-interferon-γ autoantibodies: a case report. [PDF]

BMC Infect Dis, 2023
Wang H, Lei R, Ji Y, Xu W, Zhang K, Guo X.   +5 more
europepmc   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Phytophthora ramorum is a generalist plant pathogen with differences in virulence between isolates from infectious and dead-end hosts [PDF]

, 2012
Variation in virulence was examined among isolates of Phytophthora ramorum from epidemiologically important or infectious (non-oak) and transmissive dead-end (oak) hosts from North America.
Hüberli, D., Garbelotto, M.
core  

Balancing Selection of the Intracellular Pathogen Response in Natural Caenorhabditis elegans Populations. [PDF]

Front Cell Infect Microbiol, 2021
van Sluijs L, Bosman KJ, Pankok F, Blokhina T, Wilten JIHA, Te Molder DM, Riksen JAG, Snoek BL, Pijlman GP, Kammenga JE, Sterken MG.   +10 more
europepmc   +1 more source