Proteomic Insights into Effects of a Camel Milk-Derived Peptide on Insulin Resistance: Modulation of Metabolic, Oxidative, and Signaling Pathways. [PDF]
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Transglutaminase 2 at the Interface of Gene Regulation and Antigen Processing in HLA-Restricted Immunity of Celiac Disease. [PDF]
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Macrophage Proteomic Profiling Reveals Divergent TLR4-Dependent and -Independent Responses to Kdo<sub>2</sub>-Lipid A and Lipid IVa. [PDF]
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How the Immune System Recognizes the Myriad of Antigens: Diversity of MHC (HLA) and TCR Molecules. [PDF]
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Hibernating bear serum triggers an anti-fibrotic signature in human fibroblasts, involving ECM remodeling and MAPK signaling activation. [PDF]
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The third intracellular loop (ICL3) of G protein-coupled receptors has, as a rule, a key role in their interaction with heterotrimeric G proteins. We synthesized peptides corresponding to the C-terminal region of the ICL3 (C-ICL3) of 5-hydroxytryptamine receptors of the type 1B (5-HT1BR) and 6 (5-HT6R) and studied their influence on the functional ...
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Peptide modulators of protein–protein interactions in intracellular signaling
Nature Biotechnology, 1998Signal transduction cascades involve multiple enzymes and are orchestrated by selective protein-protein interactions that are essential for the progression of intracellular signaling events. Modulators of these protein-protein interactions have been used to dissect the role of individual components of each signaling cascade. We describe several methods
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